Achaogen, a late-stage biopharmaceutical company developing innovative antibacterials addressing multidrug-resistant (MDR) gram-negative infections, announced five upcoming presentations on plazomicin at the Infectious Diseases Society of America (IDSA) IDWeek™ 2017, being held in San Diego, CA from October 4 to 8, 2017. Achaogen is developing plazomicin, its lead product candidate, to treat serious bacterial infections due to MDR Enterobacteriaceae, including carbapenem-resistant Enterobacteriaceae (CRE).
Key Poster Presentations
The following poster presentations will take place on Saturday, October 7, 2017:
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Title: |
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Improved Outcomes with Plazomicin (PLZ) Compared with Colistin (CST) in Patients with Bloodstream Infections (BSI) Caused by Carbapenem-resistant Enterobacteriaceae (CRE): Results from the CARE Study |
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Authors: |
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J.McKinnell, L.Connolly, R.Pushkin, A.Jubb, B.O’Keeffe, A.Serio, A.Smith, J.Gall, V.Riddle, K.Krause, J.Pogue |
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Title: |
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Improved Outcomes at Late Follow-up (LFU) with Plazomicin Compared with Meropenem in Patients with Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) in the EPIC Study |
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Authors: |
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Y.Golan, D.Cloutier, A.Komirenko, D.Cebrik, T.Keepers, K.Krause, L.Connolly, F.Wagenlehner |
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Title: |
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Plazomicin Versus Meropenem for Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP): Diagnosis-specific Results from the Phase 3 EPIC Study |
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Authors: |
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D.Cloutier, A.Komirenko, D.Cebrik, T.Keepers, K.Krause, L.Connolly, F.Wagenlehner |
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Additional Poster Presentations
The following poster presentations will take place on Friday, October 6, 2017:
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Title: |
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Assessment of the In Vivo Efficacy of Plazomicin (PLZ) Alone or in Combination with Meropenem (MEM) or Tigecycline (TGC) against Enterobacteriaceae (EB) Isolates Exhibiting Various Resistance Mechanisms in an Immunocompetent (I+) Murine Septicemia Model |
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Authors: |
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K. Abdelraouf, A.Kim, K.Krause, D.Nicolau |
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Title: |
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Activity of Plazomicin against Enterobacteriaceae Isolates Collected in the United States Including Isolates Carrying Aminoglycoside-Modifying Enzymes Detected by Whole Genome Sequencing |
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Authors: |
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M.Castanheira, L.Deshpande, C.Hubler, R.Mendes, A.Serio, K.Krause, R.Flamm |
