Agilent Technologies Inc. has introduced two applications that further enhance its MassHunter Workstation software and LC-MS, GC-MS and ICP-MS instruments. These new applications empower users to rapidly create targeted screening methods for food safety and forensic analysis, and to characterize intact proteins and biosimilars for biopharmaceutical research.

The Agilent MassHunter All Ions MS/MS and MassHunter BioConfirm programs are designed to increase laboratory productivity and streamline method-development processes.

The new MassHunter All Ions MS/MS software enables researchers to create acquisition methods using Agilent time-of-flight and quadrupole time-of-flight instruments. It also automatically confirms the identities of compounds with high-resolution, accurate-mass libraries and create quantitative screening methods in minutes rather than days.

MassHunter BioConfirm software provides mirror plots for the comparison of biosimilars and peak modeling deconvolution to determine the molecular weight of intact proteins. The peak-modeling algorithm removes artifacts from a mass spectrum and helps resolve overlapped peaks. The resulting (simplified) spectra then allow researchers to visualize the precision of the mass measurement and ensure the accuracy of their results. This enables rapid confirmation of intact protein sequences and modifications.

Source: Agilent Technologies Inc.