Invitrogen’s AlgiMatrix 3D Culture System is an animal–free bioscaffold for the development of high-fidelity cell culture models that are more predictive of disease states and drug responses. It is available in 96- and 24-well formats that integrate into any workflow. Cells can be inoculated directly into sterile microtiter plates preloaded with lyophilized alginate sponge without pretreatment or other preparation.
AlgiMatrix sponge is formulated using pharmaceutical-grade raw material from brown seaweed. Its pure, chemically-defined, and nontoxic macro porous structure improved lot-to-lot consistency without damage to cells. The AlgiMatrix sponge is biodegradable and is stable at room temperature.
The AlgiMatrix 3D Culture System is designed for a broad range of procedures; including multicellular tumor spheroid assays (MCTS), hepatocyte and cardiomyocyte organogenesis studies, co-culture studies, high throughput drug screening assays, and embryonic stem cell 3D differentiation.
Published in Drug Discovery & Development magazine: Vol. 12, No. 4, April, 2009, p.24.