If you’ve ever been sunburned, you’ve experienced the dreaded pain of putting on a shirt the next day. Fabric that should feel soft turns into a layer of painful pressure. That kind of pain-from what should feel like a gentle touch-is called allodynia, and it’s a fact of life for many people who suffer from…

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided “immune system” called CRISPR-Cas. At the center of this system is a surveillance complex that recognizes viral DNA and triggers its destruction. However, viruses can strike back and disable this surveillance complex…

 A new study from scientists at The Scripps Research Institute (TSRI) shows that “holes” in HIV’s defensive sugar shield could be important in designing an HIV vaccine. It appears that antibodies can target these holes, which are scattered in HIV’s protective sugar or “glycan” shield, and the question is now whether these holes can be…

Scientists at The Scripps Research Institute (TSRI) now have a high-resolution view of exactly how the experimental therapy ZMapp targets Ebola virus. The new study is also the first to show how an antibody in the ZMapp “drug cocktail” targets a second Ebola virus protein, called sGP, whose vulnerable spots had previously been unknown. “This…