The Cell Metric CLD bench top system from Solentim is optimized to provide automated cell line development (CLD) and offers an alternative approach to manually checking cell line monoclonality. The system provides unequivocal identification, qualification, and tracking of clones derived from single cells. The platform is paired with an integrated stacker system.
Using high-resolution imaging that offers three times as many pixels as previous generation cell-imaging instruments, the Cell Metric CLD system generates clear images of cells taken soon after seeding or sorting, providing confidence that a colony has grown from a single cell.
Continual imaging during early colony growth means that any wells containing multiple colonies can be quickly identified and eliminated. An automatic focus ensures that images are clear, consistent, and informative. The ability to easily distinguish between pairs of close-proximity cells and debris, coupled with uniform, clear imaging right up to the well edge, provides assurance that there is a single cell per well.
An integrated, temperature-controlled microplate stacker allows for the automated imaging of a batch of up to 10 plates at a time, with a throughput of up to 100 plates a day.
