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Electronic Lab Notebook

By R&D Editors | March 24, 2011

Accelrys, Inc., a leading scientific enterprise R&D software and services company, announced the availability of Symyx Notebook by Accelrys v. 6.6 as a  multidisciplinary electronic lab notebook (ELN) supporting analytical, process and formulation scientists working in the chemistry, manufacturing and controls (CMC) area of drug development.

The multidisciplinary Symyx Notebook by Accelrys enables cross-disciplinary teams to collaborate more effectively in moving therapeutic substances and related information from research through development to early manufacturing using efficient, validated and compliant processes. With no custom coding required, the notebook offers out-of-the-box (configurable) capabilities supporting analytical, process and formulation teams working in small and large molecule development.

“The increasing diversity and complexity of product pipelines and delivery methods in pharmaceutical development today is demanding that organizations do a better job harmonizing processes, corporate ontology, data access and knowledge capture across the R&D continuum,” said Accelrys Vice President and Chief Science Officer Dr. Frank Brown. “Harmonizing processes and data across pharmaceutical development streamlines technology transfer, accelerates drug products to clinical trials and improves the success rate of regulatory dossier submittals.”

“This industry advance for drug development is also a clear demonstration of how Accelrys’ new Enterprise R&D Architecture accelerates innovation across the R&D value chain,” said Dr. Trevor Heritage, executive vice president of software products at Accelrys. “An easily configurable, multidisciplinary notebook supporting analytical, process and formulation scientists speeds route, method and formulation selection and optimization. By streamlining information and technology transfer, Symyx Notebook by Accelrys improves process efficiency, accelerates regulatory submissions and speeds downstream scale-up to manufacturing.”

Integration of Symyx Notebook by Accelrys with existing laboratory information management systems (LIMS), scientific data management systems (SDMS), chromatography data systems (CDS) and other lab informatics solutions optimizes IP collection and transfer between scientific domains by ensuring consistent, accurate information storage and data processing. For example, integration between Symyx Notebook by Accelrys and Thermo Scientific Watson LIMS enables scientists to electronically pass bio-analytical testing results, sample lists, drug metabolism/pharmacokinetics studies and reports between the ELN and the LIMS. This reduces time-consuming manual transcription and data manipulation errors that can cause regulatory compliance issues.

For organizations working toward Quality by Design, Symyx Notebook by Accelrys centrally captures reportable information acquired over the development lifecycle, helping scientists acquire and demonstrate a better understanding of product and process variability within the established design space. Likewise, notebook support for “review by exception” methodologies shortens time to market and lowers costs by enabling quality assurance personnel to complete reviews quickly with fewer deviations and less wasted material.

Accelrys, Inc. www.accelrys.com

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