Thermo Fisher Scientific will unveil the Thermo Scientific Cellomics Comet v3.0 BioApplication on booth #1663 at the SOT 48th Annual Meeting and ToxExpo. This new application uses a cell-based imaging approach for addressing the bottleneck of rapid and accurate DNA damage assessment based on the Comet assay. This assay, also known as Single Cell Gel Electrophoresis (SCGE), is a commonly used assay to ascertain DNA damage induced in cells by acute exposure to chemicals or radiation.
The Comet BioApplication runs on the Thermo Scientific Cellomics ArrayScan VTI system (comprising instrumentation, informatics, and reagent products), and provides automatic acquisition and quantification of Comet assays. In addition the Comet BioApplication provides a more reproducible method for compound screening at lower labor costs compared with traditional manual approaches to Comet quantification, according to Thermo Fisher Scientific.
The Comet BioApplication for use on the Thermo Scientific Arrayscan VTI HCS Reader is a completely automated tool for acquiring and analyzing Comet assays to assess DNA damage in studies related to genotoxicity, ecotoxicity, and biomonitoring. With the launch of the new Cellomics Comet v3.0 BioApplication, more tests may be performed with an industry standard assay configuration. This automated, quantitative high content approach enables screening for indicators of genetic toxicity earlier in the development of therapeutic candidates and is designed to improve attrition rates, increasing efficiency and reducing costs for pharmaceutical companies.
Visit Thermo Fisher Scientific at ToxExpo 2009 at Booth #1663.