Thermo Fisher Scientific Inc., a leader in serving science, introduced Thermo Scientific High Content 2.0, an evolution of automated, quantitative cell imaging for life scientists studying cell function in oncology, neurobiology, toxicology and systems biology. High Content 2.0 builds on the success of high content screening (HCS) and high content analysis, advancing the Thermo Scientific Cellomics ArrayScan VTI, the most productive HCS platform in the industry that leverages years of customer input. High Content 2.0 offers unparalleled ease-of-use, performance and reproducibility through unique improvements in hardware and software.
New iDEV guided workflow software is just one of the innovative additions to the High Content 2.0 platform. The software is designed for the rigors of multi-user environments and provides even the occasional user with the means to efficiently and effectively develop cell imaging assays. Leveraging Thermo Fisher Scientific’s best-in-class image analysis tools, iDEV combines a more intuitive, step-by-step assay setup with an industry first “easy assay optimizer” feature that addresses multiple groups of biological states simultaneously to dramatically reduce critical assay development timelines. This unique, interactive tool allows the user to simultaneously visualize algorithmic parameter changes at the image, data and statistical level in real time.
An innovative LED light engine, designed to overcome the limitations of current bulb technology, offers unprecedented speed and reliability for screening campaigns while reducing exposure times, data variability and consumable expenses. With an extremely stable ”solid state” five-color light excitation capability, more than 10,000 hour life and low power consumption, the LED light engine offers significant improvements in large-scale data generation with a dramatically reduced environmental footprint.
High Content 2.0 also incorporates the latest optical bench from Carl Zeiss, the AxioVert Z1, which adds more than 160 years of optical expertise to improve optics and automation. With a performance benchmark of fewer than four minutes to image and analyze a typical two channel 96 well plate, the ArrayScan VTI is the fastest high content reader in its class. For the demanding researcher, the Z1 optical bench offers the confidence of a proven optical train, compared to custom optical trains, and allows for future developments as Carl Zeiss delivers new innovation.