ProFACT Proteomics and its partner in research consumables, Biotech Support Group LLC, have introduced a new reagent kit called KinaSorb, for the enrichment and isolation of kinases. In a patent pending process, ATP – the common substrate for kinases, is reversibly immobilized to metallic oxide particles, producing a single-use highly efficient enrichment method for kinase & other ATP binding proteins. The process produces kinase enrichment factors of 10-20 x relative to the non-kinase protein content, with overall kinase activity recovery up to 99%. The protocol is fast (30 minutes), scaleable and compatible with common analytical methods like electrophoresis and mass spec. The kit includes all necessary reagents for immediate use.
“We believe this product will be a generally useful tool for anyone in the kinase research field, and it fits well into our larger corporate strategy for functional proteomic profiling of kinase variants, and drug response classification,” states Matthew Kuruc, President of ProFACT Proteomics.