Researchers at the Weatherall Institute of Molecular Medicine at the University of Oxford, UK, are using Chip-Man Technologies’ Cell-IQ platform to study multipotent live cells during differentiation. The Molecular Haematology Unit is trying to understand the signalling pathways involved in haematopoiesis.
The Cell-IQ system from Chip-Man Technologies is a fully integrated continuous live cell imaging and analysis platform that can be trained to automatically quantify results. According to researchers at the institute, the very low phototoxicity achieved by the Cell-IQ allows individual cells to be tracked for up to 10 days. This compares to previous technologies which only allowed for the study of cells for up to 48 hours before phototoxic cell death. The system is also used for drug screening to identify compounds that affect the formation of aneuploid or multi-nucleated cells. A wide range of concentrations can be explored simultaneously using 96-well microplates.