The Hiden Biostream system is a research-grade mass spectrometer developed for applications in biofuel research to provide real-time analysis of dissolved gases and vapors in aqueous solutions, identifying and quantifying in real time gaseous species with molecular weights up to 300 amu. The system is fully programmable for both multiple and single species monitoring. The range of choices of inlet manifold and membrane separator styles enables an application range offering sequential measurement from single up to 80 sampling points. The system is suitable for fermentation culture analysis, monitoring gaseous and volatile organic species in media such as sea water and soils, and for evolved gas studies from microbiological systems.