Nautilus 2003 delivers new features and enhancements designed to offer greater flexibility to boost user productivity, while also easing compliance with regulatory requirements relating to the auditing of scientific data. The most significant changes over previous versions relate to functions for Result Entry and Auditing. Result Entry functionality now offers users more flexibility, including improved row ordering and switchable row/column highlighting. Barcode navigation has also been simplified for users. Auditing functionality enables audit tables of, for example, instrument or operator records in the LIMS database to be displayed in a hierarchy. This allows users to see more easily the relationships between tables and therefore view the audit trail. Increased flexibility now means that Nautilus users are also able to audit tables with primary keys that consist of more than a single field. The LIMS has been updated to operate running the Oracle 9i database, and has been fully validated on that platform. To allow customers to take advantage of the latest Windows technology, Nautilus 2003 R1 has also been validated to run on Microsoft Windows XP. It features a complete suite of tools to enable customers to address compliance with US FDA Ruling 21 CFR Part 11, which concerns electronic records and signatures.