Oxford Gene Technology (OGT), a provider of genetics research and biomarker solutions to advance molecular medicine, has produced a new, free-to-download white paper.
“When to use targeted resequencing—Choosing the right NGS method” aims to assist researchers when planning next-generation sequencing (NGS) strategies by providing a detailed review of the major resequencing methods. Comparing and contrasting method suitability, the paper also examines the significant impact of data analysis, as well as time and cost considerations. OGT has written the white paper in response to a growing demand from within its customer base and the NGS community for a balanced and comprehensive guide to targeted resequencing strategies.
Considered from both clinical research and discovery viewpoints, the paper discusses whole exome and targeted panel sequencing strategies, without bias. This includes highlighting the limitations of each approach, and offering advice on when whole genome sequencing is appropriate, providing researchers with insight to identify the most suitable method for the task at hand. Considerations are also presented on choice of capture technologies, bait design and the use of service providers for method optimisation and accessibility to meaningful results.
Download from Oxford Gene Technology: “When to use targeted resequencing—Choosing the right NGS method”