G-Biosciences’ LabSafe nucleic acid stain is a safe nucleic acid stain for the visualization of double-stranded DNA, single-stranded DNA, and RNA in agarose gels. The dyes are developed to replace toxic ethidium bromide, commonly used in gel electrophoresis.
LabSafe has been shown to be non-carcinogenic by the Ames test. The results are negative in both the mouse marrow chromophilous erythrocyte micronucleus and mouse primary spermatocyte chromosomal aberration tests.
The stain emits green fluorescence when bound to dsDNA and red fluorescence when bound to ssDNA or RNA. It has two excitation wavelength peaks when bound to nucleic acid, at 290 nm and 490 nm.