Qlucore Omics Explorer 3.1 for Mac is data analysis software designed to maximize the outcome of research by making it easy to analyze experiment data from a biological point-of-view. Examples of this are the inbuilt Gene Ontology (GO) Browser, a Gene Set Enrichment Analysis (GSEA) function, and freedom to explore data using any variable identifier: variable collapse. The GO Browser and GSEA workbench provide a complete set of results for large data sets (132 x 50000) with three mouse clicks, and in less than 30 seconds. The browser allows fast search in any ontology. After finding interesting results, the matching genes can be exported to the Variable window and used as a normal variable list. Both GO and GSEA allow the scientist to generate extensive lists of domain-specific information. The software features an open interface to R, allowing users to utilize a broader range of statistical tests, and providing greater flexibility to use existing tests in R and to write new ones.