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PerkinElmer launches next-generation DNA services

By R&D Editors | January 24, 2011

PerkinElmer,
Inc. today announced the launch of its next generation DNA sequencing
and data analysis services, to enable researchers to better explore the
genomic origins of disease.

The
new services offer scientists the capability to outsource their genome
sequencing requirements, through the company’s state-of-the-art
sequencing lab in Branford, Conn. The facility’s sequencing platforms
and software suites are backed by an Internet-enabled “private cloud”
for robust and secure “anytime, anywhere” genomic data interpretation
and analysis by customers, promoting ease of access along with maximum
data security. This “on demand” sequencing and analysis offering
provides scientists with broadened access to the benefits of
next-generation sequencing in understanding critical disease states at
the DNA level, without the burden of creating and supporting costly
in-house solutions.

According
to PerkinElmer, the new service provides life scientists with seamless,
efficient, high-value and cost-effective human and mouse exome
resequencing, which focuses on those parts of the genome where the vast
majority of disease-relevant information is derived. This approach
enables faster, actionable, disease-relevant results for researchers,
without the higher costs associated with whole-genome screening.

The
service is designed to help companies achieve results without the
associated expense of building in-house capabilities and headcount,
dealing with obsolescence in a fast-changing field, or incurring the
costs of whole-genome approaches for research paths that may not require
them.

PerkinElmer’s next generation DNA sequencing and data analysis

services comprise:

  • Collaborative project planning and consultation to define an optimized, custom-designed sequencing program
  • Comprehensive sample processing and library preparation, employing PerkinElmer automation technology and industry kits
  • Best-in-class,
    scalable sequencing platform technology – flexibility to keep pace with
    client requirements and new technology capabilities
  • Rapid turnaround times encompassing sample prep to sequence analysis
  • Guaranteed client data security – samples and data never have to leave PerkinElmer premises
  • Data
    available directly through a secure, web-based portal hosted in a
    validated private cloud environment. Data can be accessed following
    sequencing run, and archived for future analysis

The
next generation sequencing and analysis services leverage highly
automated processes powered by PerkinElmer’s JANUS Automated
Workstations. All samples and sample processing steps, including project
initiation, sample preparation, sequencing runs, data acquisition
distribution and quality control are tracked through Geospiza’s Lab
Edition-a Web-based next generation sequencing LIMS. Data analysis is
executed using Geospiza’s Analysis Edition genetic analysis and
visualization software.

Featured sequencing and analysis technologies currently deployed by PerkinElmer include:

Sample Processing and Automation

  • PerkinElmer JANUS Automated Workstations
  • PerkinElmer EnSpire Plate Readers
  • Geospiza Lab Edition

Exome Capture Options

  • Agilent SureSelect
  • Illumina TruSeq
  • Nimblegen EZ Exome

Sequencing

  • Illumina HiSeq 2000

Data Analysis

  • Geospiza Analysis Edition

For more information, visit

SOURCE: PerkinElmer Sequencing

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