EMD Millipore has launched the NovaCHOice Transfection Kit that accelerates protein production from the suspension Chinese hamster ovary (CHO) cell line. According to the company, this new reagent is the first kit optimized specifically for this popular cell line, which produces active, soluble forms of recombinant proteins used in research, drug discovery, preclinical studies, or patients.
Suspension CHO cells are widely used for recombinant protein production because they are easy to scale-up for cell culture and protein purification. However, suspension CHO cell transfection has been challenging because few optimized transfection reagents were available. EMD Millipore’s NovaCHOice transfection kit overcomes this challenge by enabling efficient delivery of DNA into the cells, resulting in high levels of gene expression and superior protein yields.
The NovaCHOice transfection kit can improve the large-scale production of therapeutic recombinant proteins, such as therapeutic monoclonal antibodies, of which kilogram-scale yields are required per batch.