Tissue IA 2.0 high performance image analysis from Leica Microsystems combines fluorescence and brightfield analysis capabilities with precision cell modeling in a single platform, providing a solution for immunohistochemical biomarker quantification.
Color separation and multi-marker colocalization functionality provides advanced insight and unbiased measurement of multiple antigen immunostaining in brightfield or fluorescent samples. Sophisticated cell modelling detects and quantifies differential expression of staining in cellular compartments, providing insight into cytoplasmic, membrane, and nuclear biomarker localization.
The dual staining capabilities enable researchers to identify cell cohorts at the molecular level. One marker can identify a population of interest and then quantify expression of a second. Algorithms can be adjusted and optimized for different markers, tissue, and protocols.
The Web-accessible interface means that users can access analysis from other locations. The Tissue IA 2.0 can process whole slides, regions of interest, or tissue microarray cores, and automatically integrate analysis results with a user’s slides. A built-in upload interface facilitates integration of algorithms from third party software solutions.
