Biosearch Technologies Inc.’s Stellaris Fish Probes are an RNA visualization method that allows detection, localization, and quantification of individual mRNA molecules at the sub-cellular level in fixed samples.
A probe set comprises multiple oligonucleotides with different sequences each with a fluorescent label that collectively bind along the same target transcript to produce a punctate signal. The probes can bind to partially degraded target mRNAs,
By enabling scientists to localize and count discrete molecules of mRNA, the technology provides results through images of RNA expression.