Sentient Knowledge Explorer 5.1 is semantic data integration and knowledge management software for healthcare and life sciences. Both KE PRO and KE Personal Edition versions are available. Key features include the ability to save data, layout only or both, and to save as type TTL, NT, N3 or RDF. An ontology import interface via Web service from NCBO BioPortal includes additional information about ontology type (OWL, OBO, UMLS) and filters for ontology selection by category, group or via text search. Additional core features include graphical and machine inference-enabled creation of well-formed Linked Data from various sources of data (TSV, CSV, XLS), graphical based creation of SPARQL queries, and a command line interface for embedding RDF creation into programs or workflows.