StarDrop 5.5 is a suite of software for guiding decisions in drug discovery, helping project teams quickly identify high-quality compounds. It works by evaluating complex data, which is often uncertain because of experimental variability or predictive error. In scoring this data, it brings confidence and intuitive simplicity to decision-making: guiding and validating the direction users take and which compounds they prioritize. Instantly interactive tools then enable users to explore ways to further improve their chosen chemistries.
Data visualization tools include interactive 3D scatter and chemical space plots. Modules include predictive ADME models, P450 metabolism prediction, automatic model building, application of 3D SAR based on Cresset’s Field technology, knowledge-based toxicity prediction through Derek Nexus, while the Nova module can be used for automatically generating new compound ideas in parallel with the BIOSTER database. The software introduces the MPO Explorer module to guide strategic decisions in drug discovery projects, guiding the development and validation of multi-parameter scoring profiles, tailored toward selecting successful compounds.