Argonne National Laboratory and Yale University researchers have used cryo-electron microscopy (cryo-EM) to obtain a high-resolution structural view of a photosystem I (PSI)-platinum nanoparticle biohybrid catalyst. This finding provides critical insights into the design of efficient systems for solar-driven hydrogen production. Background and context Photosystem I (PSI) is a protein complex integral to the photosynthetic…
New cryo-EM technology at St. Jude Children’s Research Hospital pushes boundaries of molecular imaging
For decades, structural biologists have sought to map the structures of proteins and other macromolecules within cells. Cryo-electron microscopy (cryo-EM), whose early development traces back to the 1970s, emerged as a promising technique for visualizing cells in their natural, hydrated state. But the technology’s initial inability to produce sharp images was a stumbling block in…