Research & Development World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • 2025 R&D 100 Award Winners
    • 2025 Professional Award Winners
    • 2025 Special Recognition Winners
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
  • Resources
    • Research Reports
    • Digital Issues
    • Educational Assets
    • R&D Index
    • Subscribe
    • Video
    • Webinars
    • Content submission guidelines for R&D World
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE

Tiny Soft Robot with Multilegs Paves Way for Drugs Delivery in Human Body

By City University of Hong Kong | September 26, 2018

A novel tiny, soft robot with soft caterpillar-like legs which is adaptable to adverse environment and can carry heavy load was developed. Credit: City University of Hong Kong

A novel tiny, soft robot with caterpillar-like legs capable of carrying heavy loads and adaptable to adverse environment was developed from a research led by City University of Hong Kong (CityU). This mini delivery-robot could pave way for medical technology advancement such as drugs delivery in human body.

Around the world, there has been research about developing soft milli-robots. But the CityU’s new design with multi-legs helps reduce friction significantly, so that the robot can move efficiently inside surfaces within the body lined with, or entirely immersed in, body fluids such as blood or mucus.

The research findings have been published in the latest issue of the scientific journal Nature Communications, titled “A Bio-inspired Multilegged Soft Millirobot that Functions in Both Dry and Wet Conditions”.

Bio-inspired robot design

What makes this milli-robot stand out is its hundreds of less than 1 mm long pointed legs that looks like short tiny hair. This unique design was not a random choice. The research team has studied the leg structures of hundreds of ground animals including those with 2, 4, 8 or more legs, in particular the ratio between leg-length and the gap between the legs. And from there, they got their inspiration.

“Most animals have a leg-length to leg-gap ratio of 2:1 to 1:1. So we decided to create our robot using 1:1 proportion,” explains Dr Shen Yajing, Assistant Professor at CityU’s Department of Biomedical Engineering (BME), who led the research.

The robot’s body thickness measures approximately 0.15 mm, with each conical leg measuring 0.65 mm long and the gap between the legs measuring approximately 0.6 mm, making the leg-length-to-gap ratio around 1:1. Moreover, the robot’s pointed legs have greatly reduced their contact area and hence the friction with the surface. Laboratory tests showed that the multi-legged robot has 40 times less friction than a limbless robot in both wet and dry environment.

Apart from the multi-leg design, the materials also matter. The robot is fabricated with a silicon material called polydimethylsiloxane (PDMS) embedded with magnetic particles which enables it to be remotely controlled by applying electromagnetic force. “Both the materials and the mutli-leg design greatly improve the robot’s hydrophobic property. Besides, the rubbery piece is soft and can be cut easily to form robots of various shapes and sizes for different applications,” says Professor Wang Zuankai at CityU’s Department of Mechanical Engineering (MNE) who conceived this research idea and initiated the collaboration among the researchers.

Moving at ease in harsh environment

Controlled by a magnetic manipulator used in experiments, the robot can move in both a flap propulsion pattern and an inverted pendulum pattern, meaning that it can use its front feet to flap forward as well as swinging the body by standing on the left and right feet alternately to advance respectively.

“The rugged surface and changing texture of different tissues inside the human body make transportation challenging. Our multi-legged robot shows an impressive performance in various terrains and hence open wide applications for drug delivery inside the body,” says Professor Wang.

The research team further proved that when facing an obstacle ten times higher than its leg length, the robot, with its deformable soft legs, is capable to lift up one end of its body to form an angle of up to 90-degree and cross the obstacle easily. And the robot can increase its speed by increasing the electromagnetic frequency applied.

The robot also shows a remarkable loading ability. Laboratory tests showed that the robot was capable of carrying a load 100 times heavier than itself, a strength comparable to an ant, one of the strongest Hercules in nature, or to a human being able to easily lift a 26-seated mini-bus.

The amazingly strong carrying capability, efficient locomotion and good obstacle-crossing ability make this milli-robot extremely suitable for applications in a harsh environment, for example delivering a drug to a designated spot through the digestive system, or carrying out medical inspection,” adds Dr Shen.

Before conducting further tests in animals and eventually in humans, the research teams are further developing and refining their research in three aspects, namely finding a biodegradable material, studying new shapes, and adding extra features.

“We are hoping to create a biodegradable robot in the next two to three years so it will decompose naturally after its meds delivery mission,” says Dr Shen.

Related Articles Read More >

AI in 2026: everyone is partners, everyone is suing: A timeline shows how we got here
Pancreas or pancreatic cancer with organs and tumors or cancerous cells 3D rendering illustration with male body. Anatomy, oncology, disease, medical, biology, science, healthcare concepts.
AI tool used to detect pancreatic cancer in routine CT scans in China 
NVIDIA adds Thermo Fisher to growing roster of healthcare AI partnerships at JPM
At JPM, Anthropic touts life-saving AI, and the guardrails that keep humans in charge
rd newsletter
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest info on technologies, trends, and strategies in Research & Development.
RD 25 Power Index

R&D World Digital Issues

Fall 2025 issue

Browse the most current issue of R&D World and back issues in an easy to use high quality format. Clip, share and download with the leading R&D magazine today.

R&D 100 Awards
Research & Development World
  • Subscribe to R&D World Magazine
  • Sign up for R&D World’s newsletter
  • Contact Us
  • About Us
  • Drug Discovery & Development
  • Pharmaceutical Processing
  • Global Funding Forecast

Copyright © 2026 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search R&D World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • 2025 R&D 100 Award Winners
    • 2025 Professional Award Winners
    • 2025 Special Recognition Winners
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
  • Resources
    • Research Reports
    • Digital Issues
    • Educational Assets
    • R&D Index
    • Subscribe
    • Video
    • Webinars
    • Content submission guidelines for R&D World
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE