By Christian Olsen, Business Segment Lead, Dotmatics Biologic drugs have increasingly delivered treatments for cancer and rare diseases and continue to prove effective in other wide-ranging areas, from neurological and metabolic disorders to respiratory and cardiovascular diseases. But along with the incredible potential biologics offer, there is also great pressure to discover and deliver novel…

By Haydn Boehm, Director of Product Marketing, Dotmatics Despite the buzz around artificial intelligence (AI), most industry insiders know that the use of machine learning (ML) in drug discovery is nothing new. For more than a decade, researchers have used computational techniques for many purposes, such as finding hits, modeling drug-protein interactions, and predicting reaction…

Thermo Fisher Scientific Inc. has opened its largest single-use technology manufacturing site in Greater Nashville. The $105 million, 400,000-ft2 facility enables the company to help meet rapidly growing demand for the bioprocessing materials needed to produce vaccines and breakthrough therapies for cancer and other diseases. This new site is part of Thermo Fisher’s $650 million…

Dotmatics, a maker of R&D scientific software that connects science, data and decision-making, announces the release of its Small Molecule Drug Discovery Solution, an integrated scientific R&D platform with pre-configured workflows and expanded data management capabilities. The solution helps companies innovate more easily and expedites time to deployment by leveraging best practices derived from the…

Shimadzu Scientific Instruments announces the successful commercialization of a new Amyloid Mass Spectrometry (MS) Service for the early screening of amyloid-positive individuals. This simple, research-use-only blood-based analysis method enables reliable characterization of amyloid pathology in the brain with an easy-to-acquire blood sample to assist in the evaluation and development of new pharmaceutical treatments for Alzheimer’s…

The Pistoia Alliance is announcing that it has successfully completed a proof of concept (PoC) on the digital transfer via cloud of analytical High Performance Liquid Chromatography (HPLC) methods, proving it is possible to move analytical methods securely between two different vendors and Chromatography Data Systems (CDS) vendors with ease. This PoC delivers on a…

Two Rutgers engineers specializing in the process of making drugs derived from living organisms have created an analytical tool they expect will accelerate the discovery and production of biologic drugs that are often at the cutting edge of biomedical research. In an article that is the cover story in the American Chemical Society journal, Analytical…

By Rob Taylor, Pharmaceutical Segment Manager, Malvern Panalytical Sometimes you must take things apart to rebuild them. For a child with a LEGO masterpiece, this can be heartbreaking. But in the world of pharmaceuticals, reverse-engineering drugs is crucial for the development of less expensive, more accessible generic products. Chemical and structural reverse engineering, also known…

For 2022, U.S. industrial organizations are expected to collectively invest $447 billion in R&D efforts, or about 65.8% of the total R&D monies invested by the U.S. ($679.4 billion). That industrial investment is more than all other global countries except for China. The U.S. federal government is expected to invest $181.4 billion in R&D in…

Researchers live in a world of variants — coronaviral variants are taking center stage in the media right now. But in 2022, researchers will also have to deal with the challenges of accelerating economic inflation rates, global warming, electrification of everything, fifth- and sixth-generation broadband uncertainties, declining animal and plant diversities, declining global population rates,…

PerkinElmer. will be at The American Association for Cancer Research (AACR) Annual Meeting from April 8-13 in New Orleans (booths #1009, #1851 and #909), alongside its partner companies showcasing how genomic and cellular solutions for cancer research can be used to study its mechanisms, improve biomarker discovery, and help drive targeted, therapeutic discovery leading to…

Sepha, the Northern Ireland-based manufacturer of pharmaceutical packaging and equipment, has developed a new compact small-batch blister packaging machine with full traceability and electronic data storage capabilities. The EZ Blister+ meets increased demand for 21 CFR Part 11 compliant micro-batches throughout the blister production lifecycle, from R&D right through to commercial production. It will launch…

GenNext Technologies, a growth-stage company providing biopharmaceutical drug discovery systems and services, announced the receipt of a two year, Phase II SBIR grant for a project titled “In-Cell Automated Flash Oxidation (IC-AutoFox) Protein Footprinting System.” The grant was awarded by the National Institute of General Medical Systems (NIGMS) of the U.S. Department of Health and…

Genomenon Inc., an AI-driven genomics company, announces the completion of a $20 million Series B financing round. The funds will expand the company’s commercial operations and the development of its genomic data hub, which serves genetic testing labs, hospitals, pharmaceutical, and biopharma companies. Genomenon leverages AI (Artificial Intelligence) to organize the world’s genomic knowledge and…

Thermo Fisher Scientific and Symphogen, an affiliate of the pharmaceutical company Servier, announce the continuation of their collaboration to provide biopharmaceutical discovery and development laboratories with innovative tools and streamlined workflows for efficient characterization of complex therapeutic proteins. Since the collaboration began in 2018, Symphogen has adopted new and innovative instruments and software to improve…

DuPont has launched a new online sales portal tailored to the needs of bioprocessing industry purchasers. The portal handles online sales transactions, with target lead times of less than one week. DuPont’s bioprocessing solutions enable sophisticated purifications and separations for therapeutics and diagnostics, with brands such as DuPont AMBERCHROM and DuPont AMBERLITE being well established…

EUROIMMUN, a PerkinElmer company, announces that its EUROIMMUN Anti-Dengue Virus NS1 Type 1-4 ELISA (IgG) (research use only) was cited by the U.S. Centers for Disease Control and Prevention (CDC) as part of the two-step testing algorithm guidance for pre-vaccination screening for the Dengvaxia vaccine that is used to prevent future dengue disease. According to…

Proscia, the digital and computational pathology solutions provider, and Datavant, which securely connects organizations with health data, have announced a partnership that will provide life sciences companies with digitized pathology data to power the development of novel therapeutics and diagnostics. The partnership brings together Datavant’s privacy-preserving connectivity technology and the largest U.S. health data ecosystem…

International Freezer Challenge honors Univ. of Illinois with 2021 “Winning Streak Award.” By Becky Chambers Hennessy, contributing writer (This is part two of a two-part series. Read part one, Facing sustainability in the lab, here.) The University of Illinois Urbana-Champaign is continuing a hot streak in arguably the coolest competition around. The university was recognized…

By Becky Chambers Hennessy, contributing writer Scientific research leaders are taking a long look in the mirror. They see their laboratories as home to beneficial scientific breakthroughs, in areas from epidemiology and the coronavirus to climate change and greenhouse gases. They’re also recognizing them as resource-intensive spaces with enormous carbon footprints. It’s an irony that’s…

Dr. Steve Arlington, president of The Pistoia Alliance, a global not-for-profit advocating for greater collaboration in biopharma, is calling on the pharmaceutical industry to continue building on the advances in collaboration it has built over the past two years. Digital transformation has accelerated rapidly during the pandemic, which in turn has greatly improved remote patient…

ProQR Therapeutics N.V. has announced a global licensing and research collaboration with Eli Lilly and Company (Lilly) focused on the discovery, development and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The companies will use ProQR’s proprietary Axiomer RNA editing platform to progress new drug targets toward clinical development and…

Thermo Fisher Scientific‘s clinical sequencing business and AstraZeneca announced they will co-develop next-generation sequencing (NGS)-based companion diagnostics (CDx) to support AstraZeneca’s expanding portfolio of targeted therapies. The companies will collaborate under a multiyear, global agreement. “As the pipeline of targeted therapies expands, the availability of diagnostic tools that can interrogate multiple biomarkers simultaneously will ensure…

Revelation Biosciences (Revelation), a clinical-stage life sciences company focused on the development of immunologic-based therapies for the prevention and treatment of disease, and Petra Acquisition, a special purpose acquisition company, announces they have entered into a definitive merger agreement for a business combination that will result in Revelation Biosciences becoming a publicly traded company. An…

Fusion Antibodies, a specialist in pre-clinical antibody discovery, engineering and supply for both therapeutic drug and diagnostic applications, announces that is has entered into a commercial collaboration with Eurofins, a Eurofins Scientific SE group company; a provider of products and services to the drug discovery industry. As leading global innovation-driven and customer-focused providers of antibody…