nanoTherics, a scientific medical research devices company, launched the magnefect-nano II DUO and the magnefect-LT DUO transfection systems which enable up to 192 transfection experiments to be performed in parallel. These new, compact devices offer gene transfection with improved efficiencies and cell viabilities, even with a range of difficult cell types including neuronal and primary cells. They use a unique technology which applies oscillating magnet arrays to promote magnetic nanoparticle/DNA uptake into cells to improve non-viral gene transfection, whilst maintaining high cell viability. They are simple to use with low running costs (as low as $0.1 per transfection) providing improved transfection efficiency and effectiveness over the best currently available cationic lipids at short transfection times (<30 minutes). They allow retransfection as well as adherent state transfection for user flexibility. The magnefect-nano II DUO has been launched as a higher throughput version of the magnefect-nano II, which the Company introduced in September 2011, and provides full flexibility with interchangeable 2×6, 24 and 96-well magnet array formats and variable oscillating frequency capability to enable researchers to optimise protocols to maximise transfections specifically for the cell types they are using. The magnefect-LT DUO is a lower cost system which has been launched as a higher throughput version of the magnefect-LT, which the Company introduced in January 2011, with fixed frequency oscillating frequency and fixed 2×6-well or 2×24-well or 2×96-well magnet array formats.
The magnefect-nano II DUO and the magnefect LT DUO improve transfection efficiencies with hard to transfect cells such as neuronal and primary cells and increase the throughput of the transfection experiments. They are compact systems with all of the advantages of the magnefect-nano II and the magnefect LT oscillating magnet assisted transfection devices such as the high transfection efficiencies and cell viabilities, short transfection times, and low running costs, but with higher though-put capability.
