The Thermo Scientific Varioskan Flash spectral scanning multimode reader has been certified for use with LanthaScreen assays from Invitrogen, a division of Life Technologies Corporation. The LanthaScreen assay is an advanced time-resolved fluorescence energy transfer (TR-FRET) technology for drug discovery applications. Using the time-resolved fluorescence (TRF) technology of the Varioskan Flash, biological background interference is minimized, improving sensitivity in cellular assays. The flexibility of the Varioskan Flash, in combination with the LanthaScreen platform enables rapid application of TR-FRET technology to multiple target classes across a wide range of application areas, such as second messenger, kinase or hormone receptor assays.
Advanced features of the Varioskan Flash include an automatic instrument calibration system, and automatic measurement control and diagnostics. The multiwavelength measurement feature makes it possible to accurately measure donor and acceptor emissions in a simple and time-efficient manner. The assays can be performed using low volume 384-well plates.
Source: Thermo Fisher Scientific