What can be done if the material inside a glovebox needs to be kept sterile and is hazardous?

To help answer this question, leak tightness should be reviewed. ISO10648-2 (ANSI, 1994) classifies containment enclosures based on leak tightness and provides methods for checking the leak rate of the glovebox. Many gloveboxes are extremely leak-tight and safety concerns regarding positive/negative pressure operations often become a non-issue.

This cleanroom tip was taken from “What’s in a Name? Sometimes, Not So Much,” which appeared in the July/August 2012 issue of Controlled Environments.