R&D World editors Paul Heney and Aimee Kalnoskas have their minds blown — multiple times! — in this episode, which delves into Certara’s Simcyp COVID-19 Vaccine Model, a 2021 R&D 100 Awards winner. Paul interviews Piet van der Graaf, Senior Vice President and Head of Quantitative Systems Pharmacology for Certara and learns about the genesis…

By Mark Jones Morel mushroom hunting is an interesting and enjoyable spring activity in Michigan. Finding morels is a challenge, but if you want to eat them, finding is close to the only option. It takes effort, knowledge of the woods, and a trained eye. Some friends, life-long morel hunters, introduced us to the morel…

PerkinElmer. is participating at the Bio-IT World Conference and Expo, May 3-5, in Boston, (booths #908, #912), with a focus on helping labs make well-informed and timely data-driven decisions on therapeutic candidates by leveraging cloud-based informatics solutions and strategic IT services. Helping the world’s pharmaceutical and biotech companies get a better handle on their data,…

Our co-hosts Paul Heney and Aimee Kalnoskas are talking pain in this episode — that’s some serious chronic pain. They investigate one of the most interesting recent inventions for treating this debilitating condition, something that many of us will deal with at some point in our lives. Paul and Aimee hear from Lee Hartley and Jonathan Ruais…

Los Alamos National Laboratory’s PEGASUS is a portable, ruggedized and simple-to-operate biosensor that detects a variety of important and biochemically disparate markers, including bacterial signatures, viral genetic material, toxins, and potential biothreat agents in less than 30 minutes. PEGASUS detects biomarkers from an array of environmental samples, bodily fluids, food supplies and more. Biochemical analytical…

From UCLA Samueli Newsroom A team of bioengineers at the UCLA Samueli School of Engineering has invented a novel soft and flexible self-powered bioelectronic device. The technology converts human body motions — from bending an elbow to subtle movements such as a pulse on one’s wrist — into electricity that could be used to power…

Howard University’s Chemical Engineering Department and Amgen, an independent biotechnology company, have designed an innovative academic-industry partnership meant to greatly expand opportunities for underrepresented minorities in the biotechnology and pharmaceutical industries. The partnership takes the form of a fellowship for master’s level graduate students and includes training in Amgen’s laboratories. The Chemical Engineering Department, in…

By Anne Trafton | MIT News Office Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input. However, there is often a…

Blackrock Neurotech, a brain-computer interface (BCI) technology innovator and manufacturer, has presented recently published research in Science Magazine by the University of Pittsburgh’s Rehab Neural Engineering Labs called “A brain-computer interface that evokes tactile sensations improves robotic arm control.” The research team used Blackrock’s NeuroPort System to control a bidirectional prosthetic arm to restore function…

By Jeremy Thomas, LLNL Thin-film electrodes developed at Lawrence Livermore National Laboratory have been used in human patients at the University of California, San Francisco, generating never-before-seen recordings of brain activity in the hippocampus, a region responsible for memory and other cognitive functions. In a study published today in the journal Nature Communications, surgeons at…

Southwest Research Institute has launched a joint industry project (JIP) to advance markerless 3D analysis of biomechanics for sports and medical applications. The Markerless Motion Capture Joint Industry Project (M2CJ) will leverage the SwRI-developed BIOCAP technology. BIOCAP measures human motion using machine vision, artificial intelligence (AI) deep learning, sensor fusion and biomechanical modeling. Professional and…

By Anne Stark, LLNL Lawrence Livermore National Laboratory (LLNL) scientists are leveraging their extensive experience studying the movement of airborne hazards to better understand the movement of virus-like particles through the air and to identify effective countermeasures. While the burden of airborne diseases is known to be large, its true scope is underappreciated. LLNL researchers…

By Anne Wainscott-Sargent Georgia Institute of Technology The U.S. pulp and paper industry uses large quantities of water to produce cellulose pulp from trees. The water leaving the pulping process contains a number of organic byproducts and inorganic chemicals. To reuse the water and the chemicals, paper mills rely on steam-fed evaporators that boil up…

By Aliyah Kovner The planet is comprised of continents and islands, each with unique cultures and resources. One area may be well known for growing food, another for manufacturing building materials, and yet despite their differences and distance from one another, the regions are linked by global processes. Living cells are built on a similar…

Biocatalysts are essential to the catalysis of chemical reactions for food production, pharmaceuticals, specialty chemicals, renewable energy and environmental cleanup; with their importance reflected in a growing $10 billion industrial market. But current platforms for biocatalyst discovery are too slow. Smart Microbial Cell Technology, from Los Alamos National Laboratory, is an ultra‐high‐throughput biocatalyst screening platform…

A-LabInsider’s new application lists all the academic life science labs in Europe, filtering through them to make it easier for small and medium biotech companies to discover compatible labs to do business with. The concept was to create a central place for biotech SMEs to find academic labs through the content of available websites and…

By Aliyah Kovner Researchers from Lawrence Berkeley National Laboratory (Berkeley Lab) have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing. Their approach could dramatically speed up the research and development phase for new biomanufacturing processes and get cutting-edge bio-based products such…

PLA (Polylactic acid) is one of the few biopolymers available in large quantities and at a commodity price; however, its brittleness significantly limits its use in many applications. Strategies to improve its ductility are available, however, they compromise the strength and modulus of PLA and are costly. In contrast, Oak Ridge National Laboratory’s low cost,…

A partnership between Sandia National Laboratories and the Boston firm BioBright to improve the security of synthetic biology equipment has become more relevant after the United States and others issued warnings that hackers were using the COVID-19 pandemic to increase their activities. “In the past decade, genomics and synthetic biology have grown from principally academic…

By Jennifer Chu | MIT News Office MIT engineers have designed a Velcro-like food sensor, made from an array of silk microneedles, that pierces through plastic packaging to sample food for signs of spoilage and bacterial contamination. The sensor’s microneedles are molded from a solution of edible proteins found in silk cocoons and are designed…

By Kimberly A Askey Scientists at the Department of Energy’s Oak Ridge National Laboratory and Ohio State University discovered a new microbial pathway that produces ethylene, providing a potential avenue for biomanufacturing a common component of plastics, adhesives, coolants and other everyday products. The discovery, published in Science, sheds light on a long-standing mystery about…

By Chris Adam Purdue University innovators are working on inventions to use micro-chip technology in implantable devices and other wearable products such as smart watches to improve biomedical devices, including those used to monitor people with glaucoma and heart disease. The Purdue team developed a fully implantable radio-frequency transmitter chip for wireless sensor nodes and…

By Eric Stann One day, people could monitor their own health conditions by simply picking up a pencil and drawing a bioelectronic device on their skin. In a new study, University of Missouri engineers demonstrated that the simple combination of pencils and paper could be used to create devices that might be used to monitor…

The discovery of green fluorescent protein (GFP), which is made by a jellyfish, transformed cell biology. It allowed scientists to stitch the GFP sequence to proteins from other organisms to trace their movements and interactions in living cells. Now, researchers reporting in ACS Applied Materials & Interfaces have designed peptide nanoparticles that can each glow…

On June 23, Lonza will host a free 60-minute webinar on how to gain control of bioprocesses through automated, aseptic sampling of bioreactors. Dr. Clint Pepper, director, MAST Products, will present three case studies demonstrating cost savings and enhanced throughput and Product Quality Attribute (PQA) optimization using the MAST Aseptic Sampling System, while maintaining bioreactor…