In a demonstration of “mind over matter,” a 69-year-old man with C4 AIS C spinal cord injury — whose remaining movement was largely restricted to low-amplitude muscle twitching — has piloted a virtual quadcopter merely by thinking about moving his paralyzed fingers. This achievement stems from an intracortical brain-computer interface (iBCI) primarily developed and tested…
2025 R&D layoffs tracker
Despite another solid national jobs report in December 2024—256,000 new payroll jobs and a steady 4.1% unemployment rate—companies in research-intensive fields have continued to trim their workforces in early 2025. While the broader economy shows gains in health care and retail, our tracking indicates that biotech, advanced software, and other R&D-driven sectors are strategically realigning.…
Engineered wastewater bacteria could break down microplastics
Recent scientific evidence has brought increasing attention to microplastics—plastic particles less than 5 millimeters in diameter—and their pervasive presence in our environment. While their ubiquity raises legitimate concerns, our 2024 analysis “Microplastics are bad—but ignoring science is worse” reveals that commonly cited statistics about human plastic consumption often lack rigorous scientific validation. Emerging research continues…
The battery that eats itself: Fungal power with a built-in cleanup crew
Batteries have recently come in various configurations: stretchable, as discussed in R&D World’s article “Stretchable batteries and body-conformable electronics poised to advance in 2025,” and batteries using alternative chemistries, including lithium-iron-phosphate (LFP) and sodium-ion (SIBs), among others. One battery material that might not have been on your bingo card is fungi. Researchers at Empa have…
UC Irvine researchers develop bioluminescent RNA for real-time tracking
Scientists at the University of California, Irvine, have developed a method for tagging RNA with a bioluminescent molecule, which enables real-time tracking of RNA as it moves throughout the body. This research, published in Nature Communications, could provide new insights into cellular processes, viral propagation, and memory formation in the brain. RNA is critical in…
ISS National Lab publication showcases pioneering physical science research in space
A paper published in Gravitational and Space Research reveals insights from research sponsored by the International Space Station (ISS) National Laboratory on transport phenomena. Transport phenomena are fundamental physical processes involving momentum, energy, and mass transfer. They describe how heat and matter move through their surroundings, such as how heat radiates from a stove or how a…
Color-changing, power-free sensor could boost health monitoring and improve infrastructure safety
Researchers at Chungnam National University, Daejeon, South Korea, have developed a mechanochromic strain sensor that indicates mechanical stress through changing colors — without needing an external power source. The device, described in a study published on October 15, 2024, in the journal Chemical Engineering Journal, uses magnetic nanoparticles and elastic materials to detect stretching, bending,…
25 landmark R&D-heavy tech funding rounds of 2024
[Updated December 18, 2024 with new details on Databricks] In 2024, AI-focused startups continued to dominate the funding landscape with industry leaders like OpenAI ($6.6B), xAI ($6B), and Anthropic ($4B) leading the pack. Adding to this trend, MLflow and data lakehouse pioneer Databricks recently secured a $10 billion funding round that was primarily equity-based, at…
Space Station research returns, advancing cancer and neurodegenerative therapies
Dozens of ambitious scientific investigations — including projects aiming to improve cancer detection, advance treatments for neurodegenerative diseases, and enhance respiratory therapy — have safely returned to Earth from the International Space Station (ISS). The nearly 50 experiments, sponsored by the ISS National Laboratory, were transported back on SpaceX’s 31st Commercial Resupply Services (CRS) mission…
A new study shows how fluid flow and chemicals team up to halt harmful bacteria
A new study reveals that two stressors may be better than one in preventing certain harmful bacteria from thriving in the human body. Researchers at the University of Illinois Urbana-Champaign report that physical fluid flow and the chemical presence of hydrogen peroxide can work together to halt the spread and growth of dangerous pathogens. The…
24 R&D trends that redefined 2024
In many respects, 2024 was a year of building upon the foundations laid by previous technological and scientific advances. While AI continued to evolve at a rapid clip, progress was in many ways more incremental than last year when GPT-4 redefined expectations for genAI. But AI continues to make definable improvements across a range of…
‘Giant Steps’ in genomics: How 10x is reshaping our understanding of disease
In 1959, John Coltrane’s “Giant Steps” redefined what was possible in jazz. Its unprecedented chord progression (later known as “Coltrane changes”) and relentless tempo pushed boundaries, challenging even seasoned musicians like Tommy Flanagan. The track eventually developed a reputation for being the “most feared song in jazz” for its fiendishly difficult improvisational demands. Today, genomics…
Vapourtec highlights the potential of flow biocatalysis in new review
A recent mini-review from Vapourtec showcases the vast potential of flow biocatalysis, emphasizing its role in enhancing sustainability, efficiency, and productivity in chemical synthesis. The review highlights several key publications demonstrating how flow biocatalysis is a cleaner, more cost-effective alternative to traditional organic chemistry, largely due to its use of enzymes as reagents. “The use…
New device developed to identify biomarkers of breastfeeding complications
A research team led by the University of Massachusetts Amherst has developed a sensor to detect sodium ions in breast milk — a biomarker for elevated mammary permeability. This condition is a key indicator of subclinical mastitis, an asymptomatic inflammation of the breast that can contribute to milk supply issues and potentially hinder breastfeeding for…
Argonne scientists develop sustainable aviation fuel from waste, slashing emissions by up to 70%
Argonne National Laboratory has developed a new technology that could significantly impact the aviation industry and the environment by turning waste streams into cost-competitive sustainable aviation fuel (SAF). This novel invention, dubbed “membrane-assisted anaerobic digestion” (MAAD), converts high-strength organic wastewater from sources like breweries and dairy farms into volatile fatty acids, which can be further…
Scientists explore intelligent biocomputing for neurological disease treatment
What if the combination of stem cell research, bioengineering and biocomputing could help patients with neurological damage? Researchers at the University of California, Irvine (UCI) and the University of Southern California (USC) are embarking on a research initiative to explore that very possibility. With a $2 million grant from the National Science Foundation’s Emerging Frontiers…
Where Harris and Trump stand on the future of American science
[Adobe Stock] Updated on October 20, 2024 with new details The current Biden-Harris administration and potential Republican approaches offer different visions for the future of American science. While the Biden-Harris team emphasizes investments in climate change mitigation and clean energy, conservative approaches have historically focused on deregulation and achieving energy independence through traditional energy sources.…
Explore the 2024 R&D 100 award winners and finalists
For six decades, the R&D 100 Awards have been a benchmark of achievement in science and technology, often referred to informally as “The Oscars of Innovation.” This year, we’re offering a new interactive experience, allowing you to explore the remarkable work of both winners and finalists across diverse fields. From advances in mechanical and material…
Turning ocean trash into clean fuel: Mango Materials’ strategy to create carbon-negative materials with ancient microorganisms
Methane, a potent greenhouse gas, is naturally produced in many crucial industries, such as agriculture and wastewater treatment. What if we could grab that gas before it enters the atmosphere and make something useful out of it? Mango Materials, a California-based biomanufacturing company, has invented a way to do just that. Using a special mixture…
Los Alamos National Laboratory and OpenAI to test genAI-based biological threats
Los Alamos National Laboratory and OpenAI are joining forces to conduct the world’s first real-world evaluation of AI’s potential role in biological threats. The partnership between OpenAI and Los Alamos goes beyond previous text-based assessments of AI in biological contexts. OpenAI highlighted two aspects that set this research apart, noting the “research will involve real…
How the replication crisis threatens R&D and what to do about it
Let’s say you are repeating a scientific experiment but each time you’re getting a completely different outcome. This is the frustrating reality of the “replication crisis,” a widespread problem affecting nearly every scientific discipline. “We’ve all seen in our own practices how there are many ‘researcher degrees of freedom’ that could lead to studies not…
Microbial powerhouses harness cellular energy fluctuations for bioproduction
Engineers at Washington University in St. Louis are tapping microorganisms to produce sustainable fuels, chemicals, materials, and medicines. Their latest research, published in Nature Communications, focuses on the role of ATP (adenosine-5′-triphosphate) in microbial metabolism and its role on bioproduction. Recognizing that ATP, the primary cellular energy currency, fluctuates significantly in microbes used for biomanufacturing,…
From self-driving cars to an autonomous AI/ML analytical platform for drug discovery
What do frictionless parking experiences and life-saving drugs have in common? For data scientist June Guo, the answer lies in setting AI algorithms loose on vast troves of data. Before setting his sights on human biology, Guo worked at Metropolis Technologies, a company focused on transforming the parking experience through the use of advanced computer…
Latina-led startup announces strong study results for AI-assisted technology for COPD
Samay, the maker of a patented, AI-assisted wearable device and platform to monitor lung function, announces impressive results of its trial with more than 100 subjects. Designed for COPD, the wearable device (called “Sylvee”) continuously measures air trapping and other measures of respiratory function in patients at home. This study was conducted in partnership with…
Tescan’s UniTOM HR is focus of Episode 9 of R&D 100 – The Podcast
R&D World editors Paul Heney and Aimee Kalnoskas are back, and this time they’re talking about a lot of news, in addition to the technology of the day. First, they delve into some important updates about the R&D 100 Awards for 2023 — and then dip their toes into the strange new world of AI…