By Maxwell Geiger, Associate Product Solutions Manager for the BioProcess Analytics group within IDEX Health & Science Recently, regulators have encouraged pharma and biopharma companies to incorporate the concepts of Quality by Design (QbD) and Process Analytical Technology (PAT) into drug development and manufacturing processes (1). This encouragement is part of a drive for scientists…

Since Robert Hooke’s first description of a cell in Micrographia 350 years ago, microscopy has played an important role in understanding the rules of life. However, the smallest resolvable feature, the resolution, is restricted by the wave nature of light. This century-old barrier has restricted understanding of cellular functions, interactions and dynamics, particularly at the…

By Holly Ober Engineers at UC Riverside’s Marlan and Rosemary Bourns College of Engineering have received a $600,000 grant from the National Institute of Justice to develop a test kit that can rapidly identify body fluids at crime scenes. Existing tests to detect body fluids are not very sensitive and consume relatively large amounts of…

Qosina carries a broad selection of in-stock, single-use bioprocessing components. The company provides 3D CAD models and comprehensive technical specifications, such as material safety data sheets, technical data sheets, material certification and compatibility information on most of these products. Qosina is ISO 13485, ISO 9001, ISO 22301 and ISO 14001 certified, reflecting its unwavering commitment…

[Republished from our sister publication, Design World] By Lee Teschler, Executive Editor It looks as though the U.S. Centers for Disease Control and Prevention (CDC) may end up strongly suggesting that Americans cover their faces in public until the coronavirus pandemic plays out. The Washington Post reports the recommendations now being floated would call for…

Scientists have designed a catalyst composed of very low concentrations of platinum (single atoms and clusters smaller than billionths of a meter) on the surface of titanium dioxide. They demonstrated how this catalyst significantly enhances the rate of breaking a particular carbon-oxygen bond for the conversion of a plant derivative (furfuryl alcohol) into a potential…

BTX, a division of Harvard Bioscience, has released the AgilePulse PLUS Bipolar Transfection System, an advanced electroporation system with voltage and polarity switching capabilities. The AgilePulse PLUS is ideal for automated, high performance delivery of biomolecules to mammalian cells and tissues. Maximum Efficiency. PulseAgile protocols deliver short, high-voltage pulses to porate cell membranes followed by…

Researchers at California Polytechnic State University have developed a low-cost approach that improves cell-free biotechnology’s utility for bio-manufacturing and portability for field applications. Cell-free protein synthesis (CFPS) is a biotechnology that harnesses active cellular machinery in a test tube without the presence of living cells, allowing researchers to directly access and manipulate biochemical processes. Scientists…

In 2016, the Containerized Bio-Containment System (CBCS), developed by Kansas City-based MRIGlobal — with support from HHI Corp., GPA Services L.L.C., the U.S. State Department, and The Paul G. Allen Ebola Program — was named one of the R&D 100 winners. The system is a first-of-its-kind, flyable medical transport unit and features full biocontainment. It…

Who ever said bioengineers can’t get their groove on? The Rice University team led by Antonios Mikos says otherwise with its development of a groovy method to seed sophisticated, 3D-printed tissue-engineering scaffolds with living cells to help heal injuries. The researchers are literally carving grooves into plastic threads used to build the scaffolds. The grooves…

Predicting the future is hard – predicting the future of technology is even harder. In the last 10 years, everything from entertainment to travel has been upended by the likes of Airbnb, Spotify, and Instagram – none of which even existed a decade ago – while Netflix was still delivering DVDs by mail. Now, as…

Researchers at Purdue University have been working to develop new technologies to help stop the spread of foodborne illnesses, which kill 3,000 people a year, by detecting them more efficiently. They have developed a lanthanide-based assay coupled with a laser that can be used to detect toxins and pathogenic E. coli in food samples, water…

This winter, you can carve the fresh powder of the backcountry on a pair of high-performance, eco-friendly skis designed by world-famous athletes and made from a material produced by microscopic algae. Yes, algae. The skis, made by a rather unconventional Bay Area biotech company, are a new addition to the long list of products currently…

Candida albicans, a commonly found microbe, can turn deadly when it colonizes on devices such as catheters implanted in the human body. While commonly found in healthy people, this microbe can become a serious problem for those who are seriously ill or immune-suppressed. The microbe forms a biofilm when it colonizes using, for example, a catheter…

Animal model operations to be transferred to Envigo ownership Divestment in line with Horizon’s corporate strategy to focus on its core markets Envigo, a leading global research model supplier, enters the gene-edited research model field with the addition of Horizon’s business Horizon and Envigo to collaborate on providing CRISPR screening services Horizon Discovery Group plc (LSE:…

During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this sheet forms all these derivatives, it hasn’t been possible to study the process in humans – until now. Rice bioscientist Aryeh Warmflash, graduate student…

Roughly 15% of premature births in the U.S. happen due to a pregnancy complication caused by high blood pressure, called preeclampsia. While sometimes symptoms dissipate after the mother gives birth, preeclampsia can lead to permanent damage to the kidneys or death. Purdue University researchers and colleagues, including Drs. David Reuter from Seattle Children’s Hospital and David Haas…

  A trial by researchers at Monash University could change how oxygen is administered to millions of people in intensive care units across the world. The trial found ICU patients are being given unnecessary levels of oxygen that make no difference to their recovery, and in some specific groups less oxygen may actually improve recovery…

Scientists from the National University of Science and Technology “MISIS” developed nanomaterial, which will be able to restore the internal structure of bones damaged due to osteoporosis and osteomyelitis. A special bioactive coating of the material helped to increase the rate of division of bone cells by three times. In the future, it can allow to…