2025 R&D 100 Award Winners

The 2025 R&D 100 recognizes 100 technologies selected by independent judges from academia, industry, and government. This year, Mechanical/Materials is the largest slice with 40 winners, followed by Analytical/Test with 23 and IT/Electrical with seven. The remaining 31 entries fall into Software/Services, Process/Prototyping, and Special Recognition categories, which are grouped here as Other. National labs account for 41% of the list, led by Oak Ridge National Laboratory with 17 wins and MIT Lincoln Laboratory with seven. Other frequent contributors include Lawrence Livermore National Laboratory with four wins, Sandia National Laboratories with six, and Thermo Fisher Scientific with three.

The 2025 R&D 100 winners span medical devices, manufacturing, energy, and computing, with notable activity in batteries, carbon capture, and AI-assisted inspection. Together they reflect priorities in electrification, efficiency, and reliability across industry and government. These highlights preview the full list that follows, organized by category and then alphabetically by submission name below.

Product	Organization	Category	hf:tax:rd100-category
Advanced Engineered Cellular Magmatics	Savannah River National Laboratory	Mechanical/Materials	mechanical-materials
Advanced Moderator Module	Argonne National Laboratory	Mechanical/Materials	mechanical-materials
AI-WaJe	Industrial Technology Research Institute (ITRI)	Other	other
Atlas	Nirrin Technologies	Analytical/Test	analytical-test
BILS	Industrial Technology Research Institute (ITRI)	Analytical/Test	analytical-test
BIPHASICS: Point-Source CO2 Capture with Biphasic Solvents	Oak Ridge National Laboratory	Other	other
Bleeding Materials and Enclosures product from Sandia	Sandia	Other	other
Bumpless Integration of Chiplets to AI-Optimized Fabric	MIT Lincoln Laboratory	Other	other
C3 Wind Farm Optimization Technology	National Renewable Energy Laboratory	Other	other
CHESS Thin-Film Thermoelectric Refrigeration Technology	Johns Hopkins Applied Physics Laboratory	Mechanical/Materials	mechanical-materials
CHXI–MMT	Sandia National Laboratories	Analytical/Test	analytical-test
Circu-Texfilm	SINGTEX Group	Mechanical/Materials	mechanical-materials
Copeland Oil-free Centrifugal Compressor with Aero-lift Bearing Technology	Southwest Research Institute	Mechanical/Materials	mechanical-materials
D-DIRECT Rare Earth Alloying Platform	Gadolyn, Inc.	Mechanical/Materials	mechanical-materials
Design and Development of API X65 H for hydrogen transportation	Tata Steel Limited	Mechanical/Materials	mechanical-materials
Dolacga/Ga-68 Dolacga Injection	National Atomic Research Institute (NARI)	Analytical/Test	analytical-test
DR-Weld: Digital Reality Weld and AM Simulation Tool	Oak Ridge National Laboratory	Other	other
Electro-Optical Sensor (EOS) for High-Energy Environments and Applications	Sandia National Laboratories	IT/Electrical	it-electrical
Electrochemical Graphitization in Molten Salts (E-GRIMS): A Game Changer for Sustainable Graphite Production	Oak Ridge National Laboratory	Other	other
Elevator Regenerative Power System	APh ePower Co., Ltd.	Mechanical/Materials	mechanical-materials
eMission Critical Sensor	University of Pittsburgh	IT/Electrical	it-electrical
Energy Storing Efficient Air Conditioner	National Energy Technology Laboratory	Mechanical/Materials	mechanical-materials
EpiEarth: Epidemiological & Earth-System Integrated Model for Vector-Borne Disease Risk Prediction	Los Alamos National Laboratory	IT/Electrical	it-electrical
EvoRTS: Revolutionizing AI-Chip Packaging with Flux and Void Elimination	AblePrint Technology Co., Ltd.	Other	other
ExaDigiT Digital Twin Framework	Oak Ridge National Laboratory	Other	other
Fentanyl Analog Independent Detector (FAID)	Sandia National Laboratories	Analytical/Test	analytical-test
Flex HPWH	Oak Ridge National Laboratory	Mechanical/Materials	mechanical-materials
Flexible Imaging Diffraction Diagnostic for Laser Experiments (FIDDLE)	Lawrence Livermore National Laboratory	Mechanical/Materials	mechanical-materials
Fortilife XC160 membrane	DuPont	Mechanical/Materials	mechanical-materials
Future Foundries: A Foundational Research Platform for the Integration of Emerging Systems	Oak Ridge National Laboratory; Okuma America Corporation	Other	other
Globally First Intumescent Fire-retardant Long-glass filled PP for Large Electric Vehicle Battery Pack Enclosures	SABIC	Mechanical/Materials	mechanical-materials
GM XFC Cell	General Motors	Mechanical/Materials	mechanical-materials
Griffin	Idaho National Laboratory; Argonne National Laboratory	Other	other
Hafnia Gate Dielectrics for Energy Conversion	Sandia National Laboratories	Other	other
High Energy Density Lithium-Ion Batteries with Extreme Fast Charging Capability	Oak Ridge National Laboratory; Soteria Battery Innovation Group	Mechanical/Materials	mechanical-materials
High-Rate Delay Tolerant Networking (HDTN) Software	NASA Glenn Research Center	Other	other
HyPoCap	Oak Ridge National Laboratory	Mechanical/Materials	mechanical-materials
IDEA	Lawrence Livermore National Laboratory	Other	other
KingFisher PlasmidPro Maxi Processor	Thermo Fisher Scientific	Analytical/Test	analytical-test
Lake Shore Cryotronics	Infinite Helium	Mechanical/Materials	mechanical-materials
Liberta RC deep brain stimulation (DBS) system	Abbott	Analytical/Test	analytical-test
LiCellMo, a live cell metabolic pathway analyzer	PHC Corporation	Analytical/Test	analytical-test
Looping Nylon Technique: no virgin material from recycled fiber to recycle	TTRI	Mechanical/Materials	mechanical-materials
Low Coefficient of Thermal Expansion (CTE) Molecules to Resolve Thermal Expansion Problems in Polymers	Sandia National Laboratories; University of Texas at Austin; Tetramer Technologies, Inc.	Mechanical/Materials	mechanical-materials
Low Mass and High Efficiency (LMHE) Medium-Duty Truck Engine	General Motors	Mechanical/Materials	mechanical-materials
MagicABC	Metal Industries Research & Development Centre (MIRDC)	Other	other
MAScOT: Modular, Agile, Scalable Optical Terminal	MIT Lincoln Laboratory	Mechanical/Materials	mechanical-materials
MAST-FCC – Microwave-Assisted Solids-to-Fuels & Chemical Conversion	National Energy Technology Laboratory	Other	other
MetaLitho3D	Lawrence Livermore National Laboratory	Other	other
MF-SSLC: Metal Foam Based Separate Sensible and Latent Cooling	Oak Ridge National Laboratory	Other	other
Milliken Assure (moisture barrier)	Milliken & Company	Mechanical/Materials	mechanical-materials
MnBi-based Rare-Earth-Free Permanent Magnet	Ames National Laboratory	Mechanical/Materials	mechanical-materials
Monolithic Telescopes	Lawrence Livermore National Laboratory	Analytical/Test	analytical-test
Multiflex-NR9	Nano and Advanced Materials Institute	Mechanical/Materials	mechanical-materials
Nano Extreme Temperature (NeXT) Steel: Balancing Thermal Properties, Oxidation Resistance and Extreme High Temperature Strength for Advanced Energy & Manufacturing Applications	Oak Ridge National Laboratory; Cummins, Inc.	Mechanical/Materials	mechanical-materials
Next-Gen High-Performance Polyiso Foam Insulation	Oak Ridge National Laboratory	Mechanical/Materials	mechanical-materials
NuHip	Nano and Advanced Materials Institute	Mechanical/Materials	mechanical-materials
OpenMC	Argonne National Laboratory	Other	other
Plastic Upcycled Synthetic Graphite (PLUS-Graphite)	National Energy Technology Laboratory	Mechanical/Materials	mechanical-materials
Platform to Accelerate Discovery of Tailored Industrial Enzymes (PAD-TIE)	Los Alamos National Laboratory	Other	other
PRESTO: Privacy Recommendation and Security Optimization	Oak Ridge National Laboratory	Other	other
Protected Anti-jam Tactical SATCOM (PATS) Key Management System Prototype	MIT Lincoln Laboratory	Other	other
Quantum Diamond Magnetic Cryomicroscope	MIT Lincoln Laboratory	Analytical/Test	analytical-test
Radio Frequency Situational Awareness Model	MIT Lincoln Laboratory	Other	other
Recyclable Polyester Thermosets and Reinforced Composites	Oak Ridge National Laboratory	Mechanical/Materials	mechanical-materials
RejuvaKnee meniscal repair implant	Regenity Biosciences	Mechanical/Materials	mechanical-materials
Repurposing Beverage and Fruit Waste as Biocellulose Fibre and Leather-like Film	The Hong Kong Research and Institute of Textiles and Apparel	Mechanical/Materials	mechanical-materials
Rotary Transformer for Brushless and Permanent Magnet–Free Electric Motors	Oak Ridge National Laboratory	IT/Electrical	it-electrical
SAM+J: Solid-state Additively Manufactured Transition Joints	West Virginia University	Other	other
Self-Aligned Focusing Schlieren System	NASA Langley Research Center	Analytical/Test	analytical-test
SHAD-TAGS+: Smallest High-performance Acoustic Devices Transforming Aquatic Global Solutions	Pacific Northwest National Laboratory	IT/Electrical	it-electrical
Siemens Healthineers AI Abdomen	Siemens Healthineers	Other	other
Simoa BD-Tau Advantage PLUS Assay	Quanterix Corporation	Analytical/Test	analytical-test
Simurgh	Oak Ridge National Laboratory	Other	other
spectraMRR	BrightSpec	Analytical/Test	analytical-test
Spies Hecker Permasolid Speed-TEC Speed Surfacer 5560 and Speed Clear Coat	Axalta	Mechanical/Materials	mechanical-materials
Stellar mass spectrometer	Thermo Fisher Scientific	Analytical/Test	analytical-test
SteriSEQ Rapid Sterility Testing Kit	Thermo Fisher Scientific	Analytical/Test	analytical-test
Storm-DEPART (Damage Estimate Prediction and Recovery Tool)	Idaho National Laboratory	Other	other
SynTRACS	Mitsubishi Electric Corporation	IT/Electrical	it-electrical
TESCAN AMBER X 2	TESCAN Group	Analytical/Test	analytical-test
Thermal Energy Storage Systems Including Anisotropic Thermal Conductive Carbon Fibers for Enhancing Thermal Efficiency of Phase Change Materials	Oak Ridge National Laboratory	Mechanical/Materials	mechanical-materials
Torus Spin Flywheel Energy Storage System	Torus Inc.	Mechanical/Materials	mechanical-materials
TOSSIT: Tactical Optical Spherical Sensor for Interrogating Threats	MIT Lincoln Laboratory	Analytical/Test	analytical-test
TriClip Transcatheter Edge-to-Edge Repair (TEER) System	Abbott	Analytical/Test	analytical-test
Triton AX	Protochips	Analytical/Test	analytical-test
Two Orders of Magnitude of Sensitivity Improvement for all Mass Spectrometers and Quantitative Dried Blood Cards (Thor’s Hammer)	Applied Isotope Technologies, Inc.	Analytical/Test	analytical-test
Tychem 6000 SFR	DuPont	Mechanical/Materials	mechanical-materials
Ultra-Robust Silicon All-Solid-State Battery	General Motors	Mechanical/Materials	mechanical-materials
Ultra-stable and Low-Cost Dual-Gradient Cathode for High-Performance All-Electric Vehicles	Argonne National Laboratory	Mechanical/Materials	mechanical-materials
Underwater X-ray Imaging System	Oak Ridge National Laboratory	Analytical/Test	analytical-test
Uniform, ultrahigh-temperature, stable plasma apparatus	Yale University	Other	other
Universal GridEdge Analyzer (UGA)	University of Tennessee at Knoxville	Analytical/Test	analytical-test
UV 26GNF	DuPont	Mechanical/Materials	mechanical-materials
VacuMax Vacuum Insulating Glass (VIG)	Vitro Architectural Glass	Mechanical/Materials	mechanical-materials
VisionSafe	Institute for Information Industry	Other	other
Viz ICH Plus	Viz.ai	Other	other
VL-800 Series 3D Scanner CMM	KEYENCE	Analytical/Test	analytical-test
VulcanAlloy	University of Pittsburgh	Mechanical/Materials	mechanical-materials
WiSPR: Wideband Selective Propagation Radar	MIT Lincoln Laboratory	IT/Electrical	it-electrical