Cancer’s Gene-determined ‘Immune Landscape’ Dictates Progression of Prostate Tumors
The field of immunotherapy – the harnessing of patients’ own immune systems to fend off cancer – is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumors result in distinct paths of disease progression and response to therapy. Now, researchers…
Anti-Epilepsy Drug Restores Normal Brain Activity in Mild Alzheimer’s Disease
Anti-Epilepsy Drug Restores Normal Brain Activity in Mild Alzheimer’s Disease
Study Identifies a Developmental Cause of Cardiac Hypertrophy
Investigators at Beth Israel Deaconess Medical Center (BIDMC) have identified a developmental cause of adult-onset cardiac hypertrophy, a dangerous thickening of the heart muscle that can lead to heart failure and death. Reported online in The Journal of Clinical Investigation, the new findings could lead to targeted therapies for this condition. “Genetic mutations that alter signaling…