Chronic kidney disease (CKD), an affliction characterized by progressive loss of kidney function, affects millions of people worldwide and is associated with multi-organ damage, cardiovascular disease, and muscle wasting. Just like engines, living cells require energy to run, thus the combined millions of cells forming an organ have huge energy requirements. Although the heart has…
Novel Type of Cell Death in Huntington’s Disease May Lead to Effective New Therapies
Researchers centered at Tokyo Medical and Dental University (TMDU) identify novel type of cell death in Huntington’s disease that may uncover new treatments. Tokyo – In Huntington’s disease (HD), the huntingtin gene is mutated, causing progressive neuronal death. This leads to defects in movement, behavior, and cognitive ability. Apoptosis, autophagy, and necrosis are the three…