(Okayama, Japan, 20 September 2012) – Okayama University
researchers demonstrate that cancer stem cells can be produced from
normal stem cells for new therapies to combat cancer
Authors: Ling Chen1,2,3, Tomonari Kasai1, Yueguang Li4, Yuh
Sugii1, Guoliang Jin1, Masashi Okada1, Arun Vaidyanath1, Akifumi
Mizutani1, Ayano Satoh5, Takayuki Kudoh1, Mary J. C. Hendrix6,
David S. Salomon7, Li Fu8, Masaharu Seno1
ûTitle of original paper: A model of cancer stem cells
derived from mouse induced pluripotent stem cells
ûJournal, volume, pages and year: PLoS One 7, e33544
ûDigital Object Identifier (DOI):
1 Department of Medical and Bioengineering Science, Graduate School
of Natural Science and Technology, Okayama University, Okayama,
2 Japan Society for the Promotion of Science, Tokyo, Japan.
3 Department of Pathology, Tianjin Central Hospital of Gynecology
Obstetrics, Tianjin, People’s Republic of China.
4 Department of General Surgery, Tianjin 4th Centre Hospital,
Tianjin, People’s Republic of China.
5 Multidisciplinary Division, Okayama University, Okayama,
6 Children’s Memorial Research Center, Feinberg School of
Medicine, Northwestern University, Chicago, Illinois, United States
7 Laboratory of Mammary Biology and Tumorigenesis, Center for
Cancer Research, National Cancer Institute, National Institutes of
Health, Bethesda, Maryland, United States of America.
8 State Key Laboratory of Breast Cancer Research, Department of
Breast Cancer Pathology and Research Laboratory, Cancer Hospital of
Tianjin Medical University, Tianjin, People’s Republic of