Research & Development World

  • Home Page
  • Topics
    • Aerospace
    • Archeology
    • Automotive
    • Biotech
    • Chemistry
    • COVID-19
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Market Pulse
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
      • Software
    • Semiconductors
  • 2021 R&D 100 Award Winners
    • R&D 100 Awards
    • 2020 Winners
    • Winner Archive
  • Resources
    • Digital Issues
    • Podcasts
    • Subscribe
  • Global Funding Forecast
  • Webinars

Sepsis & Septic Shock Market to Be Worth $5.9B by 2026

By Christopher Pace, Director of Infectious Diseases, GlobalData | September 19, 2017

The sepsis and septic shock space across the seven major pharmaceutical markets (7MM) of the US, 5EU (France, Germany, Italy, Spain, and the UK), and Japan is set to grow from $2.8 billion in 2016 to $5.9 billion by 2026, representing a compound annual growth rate (CAGR) of 7.9%, according to GlobalData, a recognized leader in providing business information and analytics.

Sepsis has a 78% share of annual drug revenues with approximately $2.2 billion in 2016 sales, and septic shock a 22% share with sales of $0.6 billion across the 7MM.

Sepsis is a complex disease, which not only involves a wide array of causative agents, but also results in different individual immune responses, causing various single or multiple organ dysfunction(s). The company’s latest report on sepsis and septic shock reveals that the single most important driver of market growth will be the launch of four new first-in-class pipeline drugs, BMS-936559, recAP, Traumakine, and CYT107; and three improved therapeutic options, selepressin, thrombomodulin, and cefiderocol. Furthermore, two new first-in-class medical devices will be launched in the US over the next few years: Toraymyxin and CytoSorb.

Christopher Pace, Director of the Infectious Disease team at GlobalData commented: ‘‘Opportunities will also exist for firms developing novel therapies that target comorbid conditions, with products currently in development targeting sepsis patients with disseminated intravascular coagulopathy (DIC), acute lung injury (ALI), and acute kidney injury (AKI) as examples of this approach.’’

The overall level of unmet need in the sepsis market is high. Across the 7MM the absence of licensed sepsis-specific products is the greatest unmet need across the marketplace. Drug development in sepsis and septic shock will experience a boost by anticipated improvements in clinical trial design. Pace explains: ‘‘Improving the medical community’s understanding of sepsis pathophysiology will also lead to the discovery of more clinically relevant targets and leads, along with novel biomarkers and companion diagnostics that will aid in drug development. Despite a high level of engagement in the sepsis and septic shock pipeline, no new sepsis therapeutics have reached market approval in recent years.

Developers will have to leverage innovative R&D strategies to establish the strong clinical evidence needed for approval and uptake post-licensure.’’
Some of the chief barriers of growth in the sepsis and septic shock marketplace remain the high annual cost of treatment. Although biologics have been identified as major drivers for growth, cost-conscious payers are currently putting in place considerable barriers for their reimbursement.

Pace added: ‘‘The most effective treatment is associated with early diagnosis, and so improved sepsis public awareness campaigns and physician education will help to decrease mortality primarily through early recognition and delivery of the current basic care options.’’

However it should be noted that the complexity inherent to multiple organ involvement in sepsis and septic shock continues to hinder the development of safe and tolerable agents that are effective at treating all manifestations of sepsis.

Related Articles Read More >

New dangers in the woods — and the hope that research offers us
Novel mass spectrometry solution simplifies insight gathering into macromolecular complexes
ENPICOM launches display solution to accelerate antibody selection while maximizing precision
Thermo Fisher Scientific autoimmune-testing instruments now available in the U.S.
2021 R&D Global Funding Forecast

Need R&D World news in a minute?

We Deliver!
R&D World Enewsletters get you caught up on all the mission critical news you need in research and development. Sign up today.
Enews Signup

R&D World Digital Issues

February 2020 issue

Browse the most current issue of R&D World and back issues in an easy to use high quality format. Clip, share and download with the leading R& magazine today.

Research & Development World
  • Subscribe to R&D World Magazine
  • Enews Sign Up
  • Contact Us
  • About Us
  • Drug Discovery & Development
  • Pharmaceutical Processing
  • 2022 Global Funding Forecast

Copyright © 2022 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search R&D World

  • Home Page
  • Topics
    • Aerospace
    • Archeology
    • Automotive
    • Biotech
    • Chemistry
    • COVID-19
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Market Pulse
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
      • Software
    • Semiconductors
  • 2021 R&D 100 Award Winners
    • R&D 100 Awards
    • 2020 Winners
    • Winner Archive
  • Resources
    • Digital Issues
    • Podcasts
    • Subscribe
  • Global Funding Forecast
  • Webinars