Accelrys Discovery Studio 3.5
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Discovery Studio 3.5 extends Discovery Studio’s portfolio of small-molecule ligand design biological simulation tools, including a validated ligand-profiling database for drug repurposing studies, science to assess the development potential of putative biologics and enhancements that deliver a life sciences modeling and simulation environment. The software’s ligand-profiling solution uses a spatial aggregation propensity algorithm and Developability Index licensed from MIT and validated in collaboration with Novartis Pharma AG. Science supports biotherapeutics including calculations for ranking protein-protein aggregation and improved capability to perform pH-dependent mutation energy (binding) calculations. It includes enhanced generation of receptor-ligand interaction surfaces and improved display and rendering of 3D molecular objects.
