MKS Instruments introduces its Spectra-Physics® InSight® X3+, the fourth generation of its broadly tunable, ultrafast laser platform, delivering industry-leading power, a 50% increase over the previous generation, at bioimaging wavelengths for brighter and deeper imaging. The new laser is built on the proven InSight laser platform with hundreds of peer-reviewed publications, the largest installed base in the market, and demonstrated high reliability. With its unprecedented capability, InSight X3+ is ideal for advanced multiphoton imaging in neuroscience, optogenetics, immunology and other life and health science research.

“Spectra-Physics InSight is the industry’s leading platform for multiphoton imaging, and with its unparalleled performance, the new InSight X3+ further advances our position and offering,” said Dave Allen, senior vice president and general manager for Spectra-Physics lasers. “With high peak power at long wavelengths, InSight X3+ enables deep imaging of live tissue to address the important and challenging research questions in neuroscience and other fields.”

InSight X3+ provides >3 W output power at 900 nm, >2.7 W at 1000 nm and >2.4 W at 1100nm with ultrashort pulses, exceptional beam quality and integrated dispersion precompensation to deliver highest peak powers at the sample. A second synchronized beam with >3.5 W at 1045 nm is available for multimodal and advanced imaging techniques, including second and third-harmonic generation (SHG and THG), dual-wavelength imaging, optogenetics photo-stimulation, coherent antiStokes Raman scattering (CARS) and stimulated Raman scattering (SRS) imaging. InSight X3+ is a fully automated system for seamless wavelength tuning to excite a full range of fluorophores from green fluorescent protein (GFP) to newer far red fluorophores at the longest wavelengths.

The Spectra-Physics InSight X3+ laser will be featured at SPIE BIOS and Photonics West, Moscone Center, San Francisco, February 1-6, 2020. Please visit MKS at booth #8103 at SPIE BIOS and booth #927 at SPIE Photonics West for a demonstration. For more information, please see spectra-physics.com/insight-x3plus.