Research & Development World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • Call for Nominations: The 2025 R&D 100 Awards
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
    • Explore the 2024 R&D 100 award winners and finalists
  • Resources
    • Research Reports
    • Digital Issues
    • R&D Index
    • Subscribe
    • Video
    • Webinars
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE

Molecular Printing Technology Could Recreate Chemical Environments Resembling Human Body

By Queen Mary University of London | December 27, 2017

These are fluorescently-labeled protein patterns within different types of 3-D hydrogels 5.

‘3DEAL’ is a simple and inexpensive fabrication technique able to generate complex molecular patterns within soft matter, such as hydrogels, with microscale resolution and up to centimetres in depth.

This capacity enables the possibility to engineer 3D hydrogel environments with spatial control of the chemical composition, opening the opportunity to recreate biological scenarios such as 3D molecular gradients or patterns. This could be used to design new drug screening platforms or build complex tissue engineered constructs.

The research was published in Advanced Functional Materials.

Lead researcher Professor Alvaro Mata, from Queen Mary’s School of Engineering and Materials Science, said: “The human body is largely made up of anisotropic, hierarchical, and mostly three dimensional structures. New ways to fabricate environments that can recreate physical and chemical features of such structures would have important implications in the way more efficient drugs are developed or more functional tissue and organ constructs can be engineered.”

The key design feature of 3DEAL is the use of an electrical field and a porous mask, which can be used to move and specifically localize multiple types of molecules within hydrogels with microscale resolution and within large volumes.

Gastón Primo, PhD student at Queen Mary and co-author of the paper, said: “A major advantage of the technique is its robustness and cost-effectiveness. It is simple and can be used with different types of readily available hydrogels and be patterned with different types of molecules.”

The researchers hope to create variations of the technique to enable even more complex patterning as well as focus on specific applications in tissue engineering and relevant in vitro models for biological studies.

Dietmar Hutmacher, an expert in Regenerative Medicine Science and Engineering from Queensland University of Technology, said of the research: “Fabrication of biomimetic and anisotropic hydrogels exhibiting direction-dependent structure and properties has attracted great interest in the scientific community. The Mata lab has widened the toolbox with this innovative 3DEAL technology.”

Related Articles Read More >

Caltech team 3D-prints drug depots deep inside living tissue
What could make MXene a key to ultra-precise, additive-free 3D microprinting?
Industry 4.0 Modern Factory: Facility Operator Controls Workshop Production Line, Uses Computer with Screens Showing Complex UI of Machine Operation Processes, Controllers, Machinery Blueprints
Building the thinking factory: An additive exec on AI, automation, and the skills crisis
Red Bull and Mercedes F1 cars 3D illustration, 30 Aug, 2022, Texas, EUA
6 technologies pushing Formula 1’s engineering frontier
rd newsletter
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest info on technologies, trends, and strategies in Research & Development.
RD 25 Power Index

R&D World Digital Issues

Fall 2024 issue

Browse the most current issue of R&D World and back issues in an easy to use high quality format. Clip, share and download with the leading R&D magazine today.

Research & Development World
  • Subscribe to R&D World Magazine
  • Enews Sign Up
  • Contact Us
  • About Us
  • Drug Discovery & Development
  • Pharmaceutical Processing
  • Global Funding Forecast

Copyright © 2025 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search R&D World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • Call for Nominations: The 2025 R&D 100 Awards
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
    • Explore the 2024 R&D 100 award winners and finalists
  • Resources
    • Research Reports
    • Digital Issues
    • R&D Index
    • Subscribe
    • Video
    • Webinars
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE