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FDA clears Siemens’ Symbia Intevo integrated SPECT, CT system

By R&D Editors | September 5, 2013

Siemens Healthcare has announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for Symbia Intevo—the world’s first xSPECT system, which combines the high sensitivity of single-photon emission computed tomography (SPECT) with the high specificity of computed tomography (CT). Completely integrating data from both modalities, Symbia Intevo generates high resolution and, for the first time ever, quantitative images.

Higher resolution frame of reference

In conventional SPECT/CT imaging, the SPECT image has always been reconstructed using SPECT’s low-fidelity frame of reference. For this reason, the CT resolution has been downgraded dramatically to the level of SPECT to enable the mechanical fusion of both datasets. Siemens’ new xSPECT modality reconstructs both the SPECT and CT portions of the image using the high CT frame of reference for precise, accurate alignment that facilitates the extraction and deep integration of medically relevant information. This ability is also the basis for differentiating between tissue boundaries in bone imaging. With the xSPECT Bone feature, physicians can provide additional support for detection and distinguishing between cancerous lesions and degenerative disorders.

First truly quantitative SPECT

Symbia Intevo’s precise alignment of SPECT and CT provides physicians with essential volumetric information from the CT scan, enabling accurate, consistent and reproducible quantification—a numerical indication of a tumor’s level of metabolic activity. With the xSPECT Quant feature, the physician can apply quantitative information to aid in the assessment whether a patient’s course of treatment has regressed, stabilized or grown—an assessment that is difficult to make with a purely visual assessment of the tumor.

Reduced CT dose

While Symbia Intevo uses more CT data than ever before, Siemens is still able to limit patient dose by offering combined applications to reduce exposure (CARE). Unique to Siemens, these applications include the CARE Dose4D technique, which can reduce patient CT radiation dose by up to 68%.

Increased productivity and throughput

Symbia Intevo also offers applications to improve productivity and patient throughput. For example, Siemens’ AUTOFORM collimator—a standard feature on Symbia Intevo—captures up to 26% more counts, or photons that are generated from radiotracer activity as compared to conventional collimators. This increased number of counts potentially reduces image acquisition time for increased patient throughput.

Launched in November 2011, Agenda 2013 is the initiative of the Siemens Healthcare Sector to further strengthen its innovative power and competitiveness. Specific measures, which will be implemented by the end of 2013, have been defined in four fields of action: innovation, competitiveness, regional footprint, and people development.

Source: Siemens Healthcare Sector

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