Genedata, a leading provider of advanced software solutions for drug discovery and life science research, announced a new version of Genedata Screener, a comprehensive software system for high content data analysis. Screener version 9 celebrates ten years of industry leadership in delivering cost-efficient screening data management. It features an enhanced user interface for simultaneous processing of multiple dose-response curve assays and high content image display across the entire screening cascade. These features advance the speed and accuracy of all plate-based screening at pharmaceutical companies, specialized contract research organizations, and academic screening centers. Out-of-the-box integration with leading image store solutions creates a cost-efficient HCS data management infrastructure.
“HCS has come of age. It has evolved from the domain of scientific experts to a broad application in life science research, which is fueled by a larger portfolio of affordable instruments and easier-to-use image analysis packages specific to experimental needs,” noted Dr. Othmar Pfannes, CEO of Genedata. “Genedata Screener 9 addresses this market shift with innovations in integration and visualization.
“With ten years of best practices built-in and five years specifically supporting high content data, Screener 9 is a proven enterprise hub for all plate-based screening data, with unmatched support for HCS data analysis,” continued Pfannes. “It integrates across instruments as well as HCS image analysis packages and image management systems. This integration plus enhanced visualization capabilities help to standardize and extend HCS data analysis across an organization while improving productivity without increasing data analysis cost.”
A modular system that supports the complete hit-to-lead process on a single platform, Genedata Screener scales from single plates to screens of millions of compounds. All industry-standard screening result calculations are incorporated into the system, which creates a single access point to data and images for downstream applications.
Genedata Screener 9 brings improved HCS image access and display with on-demand drill-down to original HCS images during dose-response analysis. New visualizations display complex images from multi-channeled HCS experiments including composites, masks, and overlays. They serve the in-depth qualification and systematic analysis of compound effects on cellular phenotypes. Specific enhancements include:
• High Content Analyzer now integrates with all the leading image storage solutions including PerkinElmer Columbus Image Data Management and Analysis System and Thermo Scientific Store database. Integration is also in active development with industry leaders such as the Molecular Devices MDCStore Data Management Solution.
• Condoseo now manages multiple dose-dependent HCS features in parallel and displays original HCS images alongside the dose-response curves. Its dockable user interface makes navigation easy among multiple assays, and it allows simultaneous processing of multiple assays, fitting hundreds to thousands of high-quality dose-response curves in seconds.
• Kinetics Analyzer now imports data from all time-resolved screening instruments, including label-free and automated electrophysiology experiments, and provides interactive access to kinetics traces as well as custom curve analysis methods.
Genedata Screener version 9 is available now and shipping directly from Genedata.