Research & Development World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • 2025 R&D 100 Award Winners
    • 2025 Professional Award Winners
    • 2025 Special Recognition Winners
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
  • Resources
    • Research Reports
    • Digital Issues
    • Educational Assets
    • Subscribe
    • Video
    • Webinars
    • Content submission guidelines for R&D World
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE

Laser Ignites Hot Plasma to Eradicate Tumors

By Helmholtz Zentrum Dresden-Rossendorf | September 19, 2018

When light pulses from an extremely powerful laser system are fired onto material samples, the electric field of the light rips the electrons off the atomic nuclei. For fractions of a second, a plasma is created. The electrons couple with the laser light in the process, thereby almost reaching the speed of light. When flying out of the material sample, they pull the atomic cores (ions) behind them.

In order to experimentally investigate this complex acceleration process, researchers from the German research center Helmholtz-Zentrum Dresden-Rossendorf (HZDR) have developed a novel type of diagnostics for innovative laser-based particle accelerators. Their results are now published in the journal Physical Review X.

“Our goal is an ultra-compact accelerator for ion therapy, i.e. cancer irradiation with charged particles,” says physicist Dr. Thomas Kluge from HZDR.

Besides clinics, the new accelerator technology could also benefit universities and research institutions. However, much research and development work is needed before the technology is ready for use.

The DRACO laser at the Helmholtz Center in Dresden currently achieves energies of around 50 megaelectronvolts. However, 200 to 250 megaelectronvolts are required to irradiate a tumor with protons.

Thanks to its ultrashort pulses in the range of a few femtoseconds — a time during which a light beam crosses just a fraction of a human hair — the DRACO laser achieves a power of almost one petawatt. This corresponds to one hundred times the average electrical power generated worldwide.

“We need to understand the individual processes involved in accelerating electrons and ions much better,” stresses Kluge.

Experiments at SLAC: The high-intensity laser pulse (red) is focused on a silicon grating target under 45 degrees parallel to the grating ridges. The X-ray pulses (blue) probe the laser-plasma dynamics under 90 degrees over time. The scattering patterns below show the complex particle-acceleration process. Image: © Juniks/HZDR

Together with colleagues from Dresden, Hamburg, Jena, Siegen, and the U.S., the HZDR researchers have now succeeded for the first time in observing these extremely fast processes virtually in real time at the SLAC National Accelerator Laboratory at Stanford University.

To achieve this feat, the scientists need two special lasers at the same time: the high-intensity laser at SLAC has a power of around 40 terawatts — that is, about 25 times weaker than DRACO. When striking the material sample (target), it ignites the plasma.

The second laser is an X-ray laser, which is used to precisely record the individual processes: from the ionization of the particles in the target and the expansion of the plasma, to the plasma oscillations and instabilities that occur when the electrons are heated to several million degrees Celsius, up to the efficient acceleration of the electrons and ions.

“Using the small-angle scattering method, we have realized measurements in the femtosecond range and on scales ranging from a few nanometers to several hundred nanometers,” says HZDR doctoral student Melanie Rödel, who played a leading role in the experiment.

Several years of work were necessary to access these areas and obtain clean signals on the scattering images of the X-ray laser.

“The new diagnostics for laser-based accelerators has excellently confirmed our expectations regarding its spatial and temporal resolution. We have thus paved the way for the direct observation of plasma-physical processes in real time,” says Dr. Josefine Metzkes-Ng, head of one of the participating junior research groups at the HZDR’s Institute of Radiation Physics.

Starting in 2019, the Helmholtz International Beamline for Extreme Fields (HIBEF), which the HZDR is currently setting up as part of an international collaboration at the world’s strongest X-ray laser, the European XFEL near Hamburg in Germany, will provide a next-generation experimental setup with a significantly more powerful short-pulse laser.

For the physicists involved in the experiments, a specific detail from their calculations made for a particular eye-opener. “Our targets were specially developed at the HZDR Ion Beam Center to have a kind of tiny finger structure on their surface. The laser beam scatters on this structure, resulting in a particularly large number of electrons from the corners being accelerated and crossing each other,” explains Kluge.

The fact that this detail predicted by the calculations could be discovered in the experiment, which after all lasts only ten femtoseconds, raises hopes — for instance, to be able to observe further spontaneous pattern formations (instabilities). These can be caused, for example, by the oscillation of the electrons in the electromagnetic field of the laser.

The researchers are interested in identifying instabilities that disrupt the acceleration of the electrons and ions — with the aim of avoiding them by selecting suitable targets, for example.

“However, we also know from our simulations that instabilities can even increase the efficiency of the acceleration process,” explains the physicist. “In our simulations, we have identified the Raleigh–Taylor instability, among others.”

This causes the optical laser to transfer more energy into the plasma it generates. Such “positive” instabilities could thus be an important adjusting screw to optimize the process of ion acceleration mediated by the electrons.

The laser scientists expect the new HIBEF facility to provide many more insights into plasma acceleration. This “extreme laboratory” of HZDR will provide the High Energy Density Science (HED) instrument at the European XFEL with high-power lasers.

“The X-ray pulse from the European XFEL, with which we will be measuring the processes in the plasma, is very short. We are also planning to use additional diagnostic tools so that we can optimally study the plasma oscillations, for example, see further instabilities in the experiment, and also generate them in a targeted manner,” predicts Kluge.

In this way, the HZDR researchers aim to move gradually closer to their goal of developing an ultra-compact laser accelerator for the proton therapy of cancer.

Source: Helmholtz-Zentrum Dresden-Rossendorf

Related Articles Read More >

The photon frontier: how O2O Lasercom is redefining deep-space data on Artemis II
laser reflect on optic table un quantum laboratory
2026 ultrafast laser buyer’s guide: 86 models compared
NASA R&D 100 Winner enables high-speed data transfer from space
Illustration of ultracold atoms (gold) flowing frictionlessly along a laser boundary (green), representing the quantum phenomenon of edge states.
MIT physicists directly observe frictionless ‘edge state’ flow in ultracold atoms, offering a glimpse of super-efficient electronics
rd newsletter
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest info on technologies, trends, and strategies in Research & Development.

R&D World Digital Issues

Fall 2025 issue

Browse the most current issue of R&D World and back issues in an easy to use high quality format. Clip, share and download with the leading R&D magazine today.

R&D 100 Awards
Research & Development World
  • Subscribe to R&D World Magazine
  • Sign up for R&D World’s newsletter
  • Contact Us
  • About Us
  • Drug Discovery & Development
  • Pharmaceutical Processing
  • Global Funding Forecast

Copyright © 2026 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search R&D World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • 2025 R&D 100 Award Winners
    • 2025 Professional Award Winners
    • 2025 Special Recognition Winners
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
  • Resources
    • Research Reports
    • Digital Issues
    • Educational Assets
    • Subscribe
    • Video
    • Webinars
    • Content submission guidelines for R&D World
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE