StarDrop 5.2 features a plug-in module that provides access to Cresset’s FieldAlign technology, which offers a unique, three-dimensional insight into the biological activity of compounds, as well as a flexible tool for performing automatic R-group analysis that analyzes a chemical series to interactively visualize the impact of variations to R-groups, linkers, atoms or fragments on compound properties. This is designed to help chemists to further understand the SAR of their chemistry and identify new optimization strategies. StarDrop can be used to automatically generate a range of visualizations and reports. Data can be plotted in histograms, scatter plots and radar plots included in reports. Users are not limited to in silico data from StarDrop; data can be imported from existing databases and in-house models for analysis. Data views can be linked, allowing multiple properties to be interactively explored and linked to compound structures, giving the opportunity to choose the best balanced compounds — the ones with an optimum distribution of properties.