Research & Development World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • 2025 R&D 100 Award Winners
    • 2025 Professional Award Winners
    • 2025 Special Recognition Winners
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
  • Resources
    • Research Reports
    • Digital Issues
    • Educational Assets
    • Subscribe
    • Video
    • Webinars
    • Content submission guidelines for R&D World
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE

Researchers Develop Smallest-ever Molecular Rubik’s Cube

By EPFL | April 3, 2019

EPFL researchers have created the smallest-ever version of the famous brain-teaser.

Ever since Ernő Rubik invented the Rubik’s Cube in 1974, the mathematical puzzle has tested the brains and patience of people of all ages. Two researchers working on molecular manipulation at the Laboratory of Atomic Materials (LAM) set themselves the challenge of making a version at the nanometric scale.

“One evening, we were trying to think of a simple structure to reproduce, and the idea of the Rubik’s Cube just came to us,” say Almirka Dan Norcev and Yegor Naljapäev, two PhD students at the LAM. Both are master cube-solvers and have taken part in European speedcubing competitions in the past.

To create the tiny replica, the LAM researchers first isolated atoms of six elements – including boron (B), aluminum (Al) and gallium (Ga)—to act as the “colors.” Then they linked the atoms to 27 C12N8Mg molecules. Using a scanning tunneling microscope, they were able to organize the molecules into a cube about three nanometers wide.

Unfortunately, the LAM’s Rubik’s Cube can’t be played.

“The cubes are independent for now. We didn’t create axes that would make it possible to rotate the different elements,” says Norcev.

But in light of their initial success, the two PhD students are now working on a more complex version that uses oxygen and sulfur atoms as connectors.

Related Articles Read More >

Researchers developed quantum nanosensors that can measure the temperature of a single cell
Overcoming the 100-nanometer barrier: New microbottle resonators scale up optical trapping
R&D 100 winner LLNL achieves 1,000x speed boost in 3D nanofabrication
CEA-Leti achieves 400°C CMOS fabrication milestone for 3D chip stacking
rd newsletter
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest info on technologies, trends, and strategies in Research & Development.

R&D World Digital Issues

Fall 2025 issue

Browse the most current issue of R&D World and back issues in an easy to use high quality format. Clip, share and download with the leading R&D magazine today.

R&D 100 Awards
Research & Development World
  • Subscribe to R&D World Magazine
  • Sign up for R&D World’s newsletter
  • Contact Us
  • About Us
  • Drug Discovery & Development
  • Pharmaceutical Processing
  • Global Funding Forecast

Copyright © 2026 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search R&D World

  • R&D World Home
  • Topics
    • Aerospace
    • Automotive
    • Biotech
    • Careers
    • Chemistry
    • Environment
    • Energy
    • Life Science
    • Material Science
    • R&D Management
    • Physics
  • Technology
    • 3D Printing
    • A.I./Robotics
    • Software
    • Battery Technology
    • Controlled Environments
      • Cleanrooms
      • Graphene
      • Lasers
      • Regulations/Standards
      • Sensors
    • Imaging
    • Nanotechnology
    • Scientific Computing
      • Big Data
      • HPC/Supercomputing
      • Informatics
      • Security
    • Semiconductors
  • R&D Market Pulse
  • R&D 100
    • 2025 R&D 100 Award Winners
    • 2025 Professional Award Winners
    • 2025 Special Recognition Winners
    • R&D 100 Awards Event
    • R&D 100 Submissions
    • Winner Archive
  • Resources
    • Research Reports
    • Digital Issues
    • Educational Assets
    • Subscribe
    • Video
    • Webinars
    • Content submission guidelines for R&D World
  • Global Funding Forecast
  • Top Labs
  • Advertise
  • SUBSCRIBE