A team of researchers led by Jonathan Stamler, MD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, has discovered a pathway for enhancing the self-repair efforts of injured kidneys The finding may pave the way for new drugs to stop or even reverse the progression of serious kidney disease…
New Images Show Serotonin Activating its Receptor for First Time
Serotonin (3A) receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure. Details about serotonin receptor structures could provide important clues to designing better drugs with less side effects. Now, a team of researchers from Case Western Reserve University School of Medicine…
Researchers Demonstrate ‘Random, Transistor’ Laser that can be Manipulated at Nanoscale
In the last half-century, laser technology has grown into a multi-billion-dollar global industry and has been used in everything from optical-disk drives and barcode scanners to surgical and welding equipment. Not to mention those laser pointers that entertain and confound your cat. Now, lasers are poised to take another step forward: Researchers at Case Western…
Wearable Sensors Help People Quit Smoking
Researchers at Case Western Reserve University are using wearable sensor technology to develop an automatic alert system to help people quit smoking. The smartphone app, initially limited to android-based operating systems, automatically texts 20- to 120-second video messages to smokers when sensors detect specific arm and body motions associated with smoking. There is no shortage…
Researchers Find Hidden Signals in RNAs That Regulate Protein Synthesis
Novel Therapy Delays Muscle Atrophy in Lou Gehrig’s Disease Model
Llama-Derived Nanobody Can Be Used as Potential Therapy for Hard-to-Treat Diseases
Men and Women Have Different Genetic Risk Factors for Developing Brain Cancer
Heart Disease Severity May Depend on Nitric Oxide Levels
Artificial Sweetener Splenda Could Intensify Symptoms in Those With Crohn’s Disease
In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six-week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn’s-like disease, but had no substantive effect on those…
Challenging Core Belief: Have we Misunderstood how Earth’s Solid Center Formed?
Selective Suppression of Inflammation Could Deplete HIV and Control HIV Activation
Computer Program Finds New Uses for Old Drugs
Shining a Light on the Nervous System to Thwart Disease
Soft, Flexible Origami-Inspired Robot Developed
A Case Western Reserve University researcher has turned the origami she enjoyed as a child into a patent-pending soft robot that may one day be used on an assembly line, in surgery or even outer space. Kiju Lee, the Nord Distinguished Assistant Professor of Mechanical and Aerospace Engineering, and her lab have moved from paper…
MRI Contrast Agent Locates, Distinguishes Aggressive From Slow-Growing Breast Cancer
-A new magnetic resonance imaging (MRI) contrast agent being tested by researchers at Case Western Reserve University not only pinpoints breast cancers at early stages but differentiates between aggressive and slow-growing types. “Doing both will help doctors find the right treatment,” said Zheng-Rong Lu, the M. Frank Rudy and Margaret Dormiter Rudy Professor of Biomedical…
New Machine Learning Program Shows Promise For Early Alzheimer’s Diagnosis
Researchers Receive $1.4M to Study Novel Therapeutic Approaches to Treat Intestinal Inflammation
Injectable Plant-based Nanoparticles Delay Tumor Progression
Researchers from Case Western Reserve University School of Medicine in collaboration with researchers from Dartmouth Geisel School of Medicine and RWTH Aachen University (Germany) have adapted virus particles—that normally infect potatoes—to serve as cancer drug delivery devices for mice. But in a recent article published in Nano Letters, the team showed injecting the virus particles alongside…
Injectable Plant-Based Nanoparticles Delay Tumor Progression
Researchers Call for Paradigm Shift in Type 2 Diabetes Treatment
Researchers Apply Data Science to Better Predict Effect of Weather and Other Conditions on Solar Panels
Researchers Apply Data Science to Better Predict Effect of Weather and Other Conditions
Computer Accurately Identifies, Delineates Breast Cancers on Digital Tissues Slides
A deep-learning computer network developed through research led by Case Western Reserve University was 100 percent accurate in determining whether invasive forms of breast cancer were present in whole biopsy slides. Looking closer, the network correctly made the same determination in each individual pixel of the slide 97 percent of the time, rendering near-exact delineations…