Thermo Fisher Scientific’s Orbitrap Astral mass spectrometer transforms proteomics by enabling rapid and detailed analysis of biological samples. It can identify over 8,000 protein groups from a human cell line digest in just eight minutes, significantly enhancing experimental scale and statistical power. The instrument integrates three advanced technologies: a high-resolution quadrupole mass filter, the Thermo…
CfA and NSF NRAO partner to propel black hole imaging into space
The Center for Astrophysics | Harvard & Smithsonian (CfA) and the U.S. National Science Foundation’s National Radio Astronomy Observatory (NSF NRAO) have announced a new collaboration to advance the Event Horizon Telescope (EHT) into space. This next-generation effort, called the Black Hole Explorer (BHEX) mission, aims to improve black hole imaging by combining ground-based radio…
How analytical instruments companies can overcome a challenging market
The life sciences and analytical instruments industry has been on a roller coaster for the past several years. When the COVID-19 pandemic took hold in 2020, businesses rapidly expanded to meet the moment. But four years later, the market is decidedly unusual, for lack of a better term. Many analytical instruments organizations are rife with…
Northwestern University joins global partnership to build Giant Magellan Telescope
Northwestern University has joined the international consortium constructing the Giant Magellan Telescope, a $2.54 billion observatory poised to become one of the world’s most powerful astronomical instruments. The consortium now includes 15 leading research institutions from the United States, Australia, Brazil, Chile, Israel, South Korea, and Taiwan. Northwestern brings expertise in astrophysics and artificial intelligence…
Jefferson Lab dedicates niobium-tin particle accelerator prototype
Over the past several decades, superconducting radiofrequency (SRF) particle accelerators have helped researchers probe the fundamental structure of matter. Now, scientists at the U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility are working to broaden their capabilities — and potentially reduce operating costs — by using niobium-tin coatings. Traditionally, SRF accelerators rely on cavities…
Unveiling the structure of a photosynthetic catalyst that turns light into hydrogen fuel
Argonne National Laboratory and Yale University researchers have used cryo-electron microscopy (cryo-EM) to obtain a high-resolution structural view of a photosystem I (PSI)-platinum nanoparticle biohybrid catalyst. This finding provides critical insights into the design of efficient systems for solar-driven hydrogen production. Background and context Photosystem I (PSI) is a protein complex integral to the photosynthetic…
Behind the scenes with R&D 100’s top technician of 2024
A senior scientific engineering associate at Berkeley Lab, Howdy Goudey was named the R&D 100 Technician of the Year Award winner for his pioneering work in building energy efficiency and window technologies. During his thirty years at Lawrence Berkeley National Laboratory, Goudey’s work has proven instrumental in developing sustainable building technologies, such as vacuum-insulated windows…
Endiatx aims to boldly go beyond traditional endoscopy and, eventually, redefine surgical scale
Picture a nuclear-powered surgical robot targeting glioblastoma. Or imagine hijacking a botfly larva to perform delicate internal interventions. These scenarios may sound far out, but Endiatx CEO Torrey Smith talks about them as if describing an ambitious home improvement project — challenging but entirely feasible with the right approach and tools. Though these scenarios sound…
UC Irvine researchers uncover mechanisms enhancing superconductivity in iron-based material
Scientists at the University of California, Irvine, have discovered atomic-scale processes that enhance superconductivity in iron selenide (FeSe), an iron-based material. The findings, published in Nature, could inform future advancements in quantum computing, electronics, and other technologies. UC Irvine’s Materials Research Institute (IMRI) researchers imaged atomic vibrations using advanced spectroscopy instruments. They identified new phonons…
AI agents: The next big thing in science — eventually?
If you read much about AI, you’ve likely noticed the growing number of models capable of “reasoning” and acting autonomously. This isn’t just about chatbots; it’s transforming scientific discovery. Google DeepMind recently launched a 15-day weather forecasting agent, bringing new levels of accuracy to complex atmospheric modeling. OpenAI’s latest reasoning model, o1, has demonstrated potential…
Researchers report enhanced seawater evaporation using modified clay-hydrogel system
Researchers from the University of South Australia, in collaboration with Chinese colleagues, have documented an 18.8% increase in seawater evaporation rates compared to pure water through the integration of mineral materials into photothermal hydrogel evaporators. The study, published in Advanced Materials, demonstrates a new approach to interfacial solar-powered desalination that addresses both surface salt accumulation…
Argonne National Laboratory joins New Energy Frontier Research Center to advance next-generation electronics
Ten centers across nine states will receive a share of $118 million in funding to advance fundamental energy research. Argonne National Laboratory scientists will contribute to a new Energy Frontier Research Center (EFRC), which will be funded by the DOE Office of Science’s Basic Energy Sciences. Ten new and some renewed centers will receive a…
4 DNA and genomics advances recognized in R&D 100 Awards in 2024
DNA analysis has undergone a quiet revolution in recent years thanks to next-generation sequencing (NGS) advances. In addition to its potential in medicine, NGS is taking off in forensic science. This technology allows for more detailed and accurate genetic analysis, improving the resolution of criminal cases and helping solve cold cases that have remained unsolved…
24 R&D trends that redefined 2024
In many respects, 2024 was a year of building upon the foundations laid by previous technological and scientific advances. While AI continued to evolve at a rapid clip, progress was in many ways more incremental than last year when GPT-4 redefined expectations for genAI. But AI continues to make definable improvements across a range of…
‘Giant Steps’ in genomics: How 10x is reshaping our understanding of disease
In 1959, John Coltrane’s “Giant Steps” redefined what was possible in jazz. Its unprecedented chord progression (later known as “Coltrane changes”) and relentless tempo pushed boundaries, challenging even seasoned musicians like Tommy Flanagan. The track eventually developed a reputation for being the “most feared song in jazz” for its fiendishly difficult improvisational demands. Today, genomics…
Is your R&D in the ‘Valley of Death’?
Every year, thousands of groundbreaking ideas emerge from research labs and universities, brimming with the potential to reshape industries. Yet, a significant number of these innovations never see the light of day. They fall into the abyss ominously termed the “Valley of Death,” which, as a paper in Science Direct puts it, “is an unfavorable…
Thermo Fisher Scientific unveils integrated multimodal electron microscope at European Microscopy Congress 2024
Thermo Fisher Scientific has introduced the Thermo Scientific Iliad (S)TEM, a fully integrated multimodal scanning transmission electron microscope designed to advance research in materials science by offering atomic-level insights into complex modern materials. Revealed at the European Microscopy Congress 2024 in Copenhagen, the Iliad (S)TEM combines inventive technologies such as electron energy loss spectroscopy (EELS)…
ISS Research could pave the way for earlier cancer diagnosis
Researchers are exploring the potential of the International Space Station’s microgravity environment to improve the sensitivity of biosensors used for cancer detection, leading them to investigate a compelling possibility: Could the key to earlier cancer detection lie in the behavior of bubbles in space? Studies on the ISS are showing that it just might, as…
New cryo-EM technology at St. Jude Children’s Research Hospital pushes boundaries of molecular imaging
For decades, structural biologists have sought to map the structures of proteins and other macromolecules within cells. Cryo-electron microscopy (cryo-EM), whose early development traces back to the 1970s, emerged as a promising technique for visualizing cells in their natural, hydrated state. But the technology’s initial inability to produce sharp images was a stumbling block in…
University of California transforms life science research procurement with Labviva
The University of California (UC) has selected Labviva, an AI-powered procurement platform, to enhance its life science research and procurement operations across all ten campuses. Initially deployed at UC San Diego in 2022, the platform went live at UC Merced in September 2024. This collaboration aims to streamline procurement processes for faculty, researchers, and staff,…
Decoding Lubrizol’s AI-driven beauty R&D
At Lubrizol, the quest for better skincare has taken a decidedly high-tech turn, culminating in the recent opening of a new Beauty Research Institute in Shanghai. This facility will serve as a global hub for in-vivo beauty testing. It will also aid the company in developing next-generation ingredients designed to cater to the specific needs…
Robots run the lab, biologists design the experiments
Parallel Bio’s head of technology shares a vision for faster, cheaper, and better biological research with human organoids. Ari Gesher, Parallel Bio’s new head of technology, may be new to biotech, but that’s not stopping him from thinking big about disrupting the status quo in biological research. The biotech startup is betting on automation and…
What are the applications of spectrophotometer?
A spectrophotometer is an instrument that measures the interaction of light with matter across different wavelengths of the electromagnetic spectrum. It works by passing a beam of light through a sample and comparing the intensity of the light before and after it interacts with samples including”solutions, transparent or opaque solids, such as polished glass, or…
‘Slinky’ nanocrystals change color, potentially boosting microelectronics and cell research
A new class of nanoscale materials that act like microscopic mood rings, changing color with temperature, could help measure temperature at the tiniest scales, with potential applications in electronics, biology, and beyond. Published in Advanced Materials, this research from scientists at the University of California, Irvine involves a one-dimensional nanoscale material known as indium selenium…
Explore the 2024 R&D 100 award winners and finalists: The Oscars of Innovation at your fingertips
For six decades, the R&D 100 Awards have been a benchmark of achievement in science and technology, often referred to informally as “The Oscars of Innovation.” This year, we’re offering a new interactive experience, allowing you to explore the remarkable work of both winners and finalists across diverse fields. From advances in mechanical and material…